Evidence map›Paper›PMID 33468693›Full record

ArticlemBio2021

Chlamydia trachomatis TmeA Directly Activates N-WASP To Promote Actin Polymerization and Functions Synergistically with TarP during Invasion.

Gabrielle Keb, Joshua Ferrell, Kaylyn R Scanlon, Travis J Jewett, Kenneth A Fields

Open access · goldAbstract read
In one paragraph

Article in mBio, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers.

0numbers the graph read from it
0cells of the map it votes in
33citing papers in PubMed
3.9field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

33 citing papers in PubMed, 37 citations in OpenAlex.

  1. Article
  2. Review
  3. ThemBio · 2026
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  7. Complete deletion of theInfection and immunity · 2025
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  8. ThebioRxiv : the preprint server for biology · 2025
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  9. mSphere · 2025
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  10. The N-terminus of theMicrobiology spectrum · 2025
    Article
  11. Chlamydia trachomatis invasion: a duet of effectors.Biochemical Society transactions · 2025
    Review
  12. The N-terminus of thebioRxiv : the preprint server for biology · 2024
    Article
  13. Article
  14. mBio · 2024
    Article
  15. Article
  16. Review
  17. Dynamin-dependent entry ofResearch square · 2023
    Article
  18. Type III Secretion inMicrobiology and molecular biology reviews : MMBR · 2023
    Review
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Gabrielle KebDepartment of Microbiology, Immunology, and Molecular Genetics, University of Kentucky College of Medicine, Lexington, Kentucky, USA.
Joshua FerrellDepartment of Microbiology, Immunology, and Molecular Genetics, University of Kentucky College of Medicine, Lexington, Kentucky, USA.
Kaylyn R ScanlonDivision of Immunity and Pathogenesis, Burnett School of Biomedical Sciences, College of Medicine, University of Central Florida, Orlando, Florida, USA.
Travis J JewettDivision of Immunity and Pathogenesis, Burnett School of Biomedical Sciences, College of Medicine, University of Central Florida, Orlando, Florida, USA.
Kenneth A FieldsDepartment of Microbiology, Immunology, and Molecular Genetics, University of Kentucky College of Medicine, Lexington, Kentucky, USA Ken.fields@uky.edu.ORCID 0000-0002-4703-6778
University of Kentucky · USUniversity of Central Florida · US

Funding

Type III exported effectors of Chlamydia trachomatisR01AI065530 · NIAID · UNIVERSITY OF MIAMI SCHOOL OF MEDICINE · PI FIELDS, KENNETH A · 2005 to 2021
$5.7M
Molecular Analysis of the Chlamydia trachomatis virulence factor TarpR01AI139242 · NIAID · UNIVERSITY OF CENTRAL FLORIDA · PI JEWETT, TRAVIS JAMES · 2019 to 2022
$2.3M
Chlamydia trachomatis Secreted Effector Proteins: Infection Properties and Identification of Host TargetsF31AI147417 · NIAID · UNIVERSITY OF KENTUCKY · PI KEB, GABRIELLE · 2019 to 2021
$74k
NIAID NIH HHS F31 AI147417NIAID NIH HHS R01 AI065530NIAID NIH HHS R01 AI139242
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Actin-Related Protein 2Actin-Related Protein 3ActinsBacterial Proteinscdc42 GTP-Binding ProteinCell LineChlamydia trachomatisCytoskeletonEpithelial CellsGene Expression RegulationHeLa CellsHost-Pathogen InteractionsHumansMolecular ChaperonesPolymerizationrac1 GTP-Binding ProteinActin-Related Protein 2Actin-Related Protein 3ActinsACTR2 protein, humanACTR3 protein, humanBacterial Proteinscdc42 GTP-Binding ProteinCDC42 protein, humanMolecular Chaperonesrac1 GTP-Binding ProteinRAC1 protein, humanType III Secretion SystemsWASL protein, humanWiskott-Aldrich Syndrome Protein, NeuronalFLAEMFRAEMN-WASPtype III secretion

Identifiers

PMID33468693
PMCPMC7845632
OpenAlexW3125123812

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.