ArticlemBio2021
At Least Seven Distinct Rotavirus Genotype Constellations in Bats with Evidence of Reassortment and Zoonotic Transmissions.
Article in mBio, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers, 2 of them syntheses that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
34 citing papers in PubMed, 2 syntheses or guidelines pooled it, 53 citations in OpenAlex.
- Unveiling the hidden threats: a review of pathogen diversity and public health risks from bats, rodents, and non-human primates in Zambia (1990-2022).Frontiers in public health · 2024Pooled it
- Viral Co-Infection in Bats: A Systematic Review.Viruses · 2023Pooled it
- Global status, bias risks, and ecological integration of wild bat and rodent virome research.One health (Amsterdam, Netherlands) · 2026Review
- Identification of a putative novel rotavirus A VP4 genotype in bats from an urban Atlantic Forest, in the metropolitan region of Rio de Janeiro State, Southeastern Brazil.Archives of virology · 2026Article
- Article
- Zoonotic Spillover of a Canine-like Rotavirus A G3P[3] Strain in a Brazilian Child.Tropical medicine and infectious disease · 2026Article
- Review
- Novel 20th century rotavirus alphagastroenteritidis strains identified in formalin-fixed and ethanol-preserved museum specimens.Molecular biology and evolution · 2026Article
- Hidradenitis suppurativa patients exhibit a distinctive and highly individualized skin virome.mSystems · 2026Article
- Viral diversity, ecological interconnectedness, and the identification of mammalian chuviruses in Australian microbats.Virus evolution · 2026Article
- A wide diversity of viruses detected in African mammals involved in the wild meat supply chain.PLoS pathogens · 2025Article
- Article
- Diversity and Potential Cross-Species Transmission of Rotavirus A in Wild Animals in Yunnan, China.Microorganisms · 2025Article
- Emergence of two novel viruses in Tibetan pigs with porcine diarrheal disease on the Tibetan plateau of southwest China.Frontiers in veterinary science · 2025Article
- Article
- Genetic and antigenic characterization of two diarrhoeicdominant rotavirus A genotypes G3P[12] and G14P[12] circulating in the global equine population.The Journal of general virology · 2024Article
- Analyses and Insights into Genetic Reassortment and Natural Selection as Key Drivers ofViruses · 2024Article
- Whole-genome characterization of common rotavirus strains circulating in Vellore, India from 2002 to 2017: emergence of non-classical genomic constellations.Gut pathogens · 2023Article
- Genome analysis of the novel putative rotavirus species K.Virus research · 2023Article
- Genetic Diversity of Rotaviruses Circulating in Pediatric Patients and Domestic Animals in Thailand.Tropical medicine and infectious disease · 2023Review
Corrections and comments
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Authors and funding
24 authors at 10 institutions in 8 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Bats host many viruses pathogenic to humans, and increasing evidence suggests that rotavirus A (RVA) also belongs to this list. Rotaviruses cause diarrheal disease in many mammals and birds, and their segmented genomes allow them to reassort and increase their genetic diversity. Eighteen out of 2,142 bat fecal samples (0.8%) collected from Europe, Central America, and Africa were PCR-positive for RVA, and 11 of those were fully characterized using viral metagenomics. Upon contrasting their genomes with publicly available data, at least 7 distinct bat RVA genotype constellations (GCs) were identified, which included evidence of reassortments and 6 novel genotypes. Some of these constellations are spread across the world, whereas others appear to be geographically restricted. Our analyses also suggest that several unusual human and equine RVA strains might be of bat RVA origin, based on their phylogenetic clustering, despite various levels of nucleotide sequence identities between them. Although SA11 is one of the most widely used reference strains for RVA research and forms the backbone of a reverse genetics system, its origin remained enigmatic. Remarkably, the majority of the genotypes of SA11-like strains were shared with Gabonese bat RVAs, suggesting a potential common origin. Overall, our findings suggest an underexplored genetic diversity of RVAs in bats, which is likely only the tip of the iceberg. Increasing contact between humans and bat wildlife will further increase the zoonosis risk, which warrants closer attention to these viruses.
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