Evidence map›Paper›PMID 33468684›Full record

ArticlemBio2021

Sterilization by Adaptive Immunity of a Conditionally Persistent Mutant of Mycobacterium tuberculosis.

Catherine Vilchèze, Steven A Porcelli, John Chan, William R Jacobs

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in mBio, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.3field-weighted citation impact, top 44% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 5 citations in OpenAlex.

  1. Mycobacteriophage-mediated gene transfer enables in vitro drug screening and in vivo tracking ofProceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Catherine VilchèzeDepartment of Microbiology and Immunology, Albert Einstein College of Medicine, Bronx, New York, USA.
Steven A PorcelliDepartment of Microbiology and Immunology, Albert Einstein College of Medicine, Bronx, New York, USA.
John ChanDepartment of Microbiology and Immunology, Albert Einstein College of Medicine, Bronx, New York, USA.
William R JacobsDepartment of Microbiology and Immunology, Albert Einstein College of Medicine, Bronx, New York, USA william.jacobs@einsteinmed.org.ORCID 0000-0003-3321-3080
Albert Einstein College of Medicine · US

Funding

Validation and Application of a Model for Human-like TB Latency in RabbitsU19AI111276 · NIAID · RBHS-NEW JERSEY MEDICAL SCHOOL · PI ALLAND, DAVID, ALLAND, DAVID · 2014 to 2020
$23.3M
Molecular Genetic Analysis of Mycobacterium TuberculosisR37AI026170 · NIAID · ALBERT EINSTEIN COL OF MED YESHIVA UNIV · PI WILLIAM Robert JACOBS · 2004 to 2026
$7.7M
MOLECULAR GENETIC ANALYSIS OF MYCOBACTERIUM TUBERCULOSISR01AI026170 · NIAID · YESHIVA UNIVERSITY · PI JACOBS, WILLIAM ROBERT · 1989 to 2022
$7.1M
Generation of a Complete Set of Precise Null Bar-Coded Deletion Mutants of Mycobacterium tuberculosisR24AI134650 · NIAID · ALBERT EINSTEIN COLLEGE OF MEDICINE, INC · PI Shazia Hamid, WILLIAM Robert JACOBS · 2017 to 2026
$5.6M
Immunoregulation by indoleamine 2,3-dioxygenases in tuberculosisR01AI137344 · NIAID · RBHS-NEW JERSEY MEDICAL SCHOOL · PI CHAN, JOHN R., PORCELLI, STEVEN A · 2018 to 2022
$4.0M
IgM in the regulation of TB immunityR01AI139297 · NIAID · RUTGERS BIOMEDICAL AND HEALTH SCIENCES · PI CHAN, JOHN R. · 2019 to 2023
$3.6M
Shortening Tuberculosis Chemotherapies using N-acetylcysteineR21AI132940 · NIAID · ALBERT EINSTEIN COLLEGE OF MEDICINE, INC · PI JACOBS, WILLIAM ROBERT · 2018 to 2019
$459k
NIAID NIH HHS R01 AI026170NIAID NIH HHS R01 AI137344NIAID NIH HHS R01 AI139297NIAID NIH HHS R21 AI132940NIAID NIH HHS R24 AI134650NIAID NIH HHS R37 AI026170NIAID NIH HHS U19 AI111276
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Adaptive ImmunityGene DeletionImmunocompromised HostAnimalsArginineFemaleHomeodomain ProteinsHumansImmunocompetenceLeucineMethionineMiceMice, Inbred C57BLMice, KnockoutMycobacterium tuberculosisPantothenic AcidArginineHomeodomain ProteinsLeucineMethioninePantothenic AcidRAG-1 proteinconditional persistenceMycobacterium tuberculosissterilizing immunity

Identifiers

PMID33468684
PMCPMC7845640
OpenAlexW3123250062

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.