Evidence map›Paper›PMID 33468683›Full record

ArticlemBio2021

RanDeL-Seq: a High-Throughput Method to Map Viral

Timothy Notton, Joshua J Glazier, Victoria R Saykally, Cassandra E Thompson, Leor S Weinberger

Open access · goldAbstract read
In one paragraph

Article in mBio, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.1field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 7 citations in OpenAlex.

  1. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Timothy NottonGladstone Center for Cell Circuitry, Gladstone Institutes, San Francisco, California, USA.
Joshua J GlazierGladstone Center for Cell Circuitry, Gladstone Institutes, San Francisco, California, USA.
Victoria R SaykallyGladstone Center for Cell Circuitry, Gladstone Institutes, San Francisco, California, USA.
Cassandra E ThompsonGladstone Center for Cell Circuitry, Gladstone Institutes, San Francisco, California, USA.
Leor S WeinbergerGladstone Center for Cell Circuitry, Gladstone Institutes, San Francisco, California, USA leor.weinberger@gladstone.ucsf.edu.ORCID 0000-0002-9987-6357
Gladstone Institutes · US

Funding

A Gene Drive Therapy for HIV: Single-Administration Intervention for High-RiskGroupsDP1DA051144 · NIDA · J. DAVID GLADSTONE INSTITUTES · PI WEINBERGER, LEOR S · 2020 to 2024
$5.7M
Developing Transmissible Antivirals by Exploiting Gene-Expression CircuitryDP2OD006677 · OD · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI WEINBERGER, LEOR S · 2009 to 2009
$2.3M
Stochastic Gene Expression in Retroviral LatencyR01AI109593 · NIAID · J. DAVID GLADSTONE INSTITUTES · PI WEINBERGER, LEOR S · 2014 to 2018
$2.2M
Development of a Technology Platform for Engineering Single-Administration HIV TherapeuticsR56AI145018 · NIAID · J. DAVID GLADSTONE INSTITUTES · PI WEINBERGER, LEOR S · 2019 to 2019
$976k
NIAID NIH HHS R01 AI109593NIAID NIH HHS R56 AI145018NIDA NIH HHS DP1 DA051144NIH HHS DP2 OD006677
6 · The paper itself

Abstract

It has long been known that noncoding genomic regions can be obligate

Indexed as

Gene Expression Regulation, ViralGenes, ViralGenome, ViralBase SequenceChromosome MappingGene LibraryHEK293 CellsHIV-1HumansSequence DeletionVirus ReplicationZika Virusbiotechnologyhuman immunodeficiency virussynthetic biology

Identifiers

PMID33468683
PMCPMC7845639
OpenAlexW3123230932

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.