ArticleStroke and vascular neurology2021
Ambulatory blood pressure profile and stroke recurrence.
Article in Stroke and vascular neurology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
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Who cites it
6 citing papers in PubMed.
- Sleep Disorders and Stroke: Pathophysiological Links, Clinical Implications, and Management Strategies.Medical sciences (Basel, Switzerland) · 2025Review
- Associations between obesity class and ambulatory blood pressure curves in African American women.Obesity (Silver Spring, Md.) · 2025Article
- Feasibility of ambulatory blood pressure monitoring to predict cardiovascular outcome in stroke survivors.Hypertension research : official journal of the Japanese Society of Hypertension · 2024Article
- Impact of blood pressure variability and cerebral small vessel disease: A systematic review and meta-analysis.Heliyon · 2024Article
- Minor stroke patients with mild-moderate diastolic blood pressure derive greater benefit from dual antiplatelet therapy.Hypertension research : official journal of the Japanese Society of Hypertension · 2024Observational
- Association between the geriatric nutritional risk index and the risk of stroke in elderly patients with hypertension: A longitudinal and cohort study.Frontiers in nutrition · 2022Article
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Authors and funding
17 authors.
Funding
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Abstract
objectivesTo establish a new ambulatory blood pressure (ABP) parameter (24-hour ABP profile) and evaluated its performance on stroke outcome in ischaemic stroke (IS) or transient ischaemic attack (TIA) patients.
methodsThe prospective cohort consisted of 1996 IS/TIA patients enrolled for ABP monitoring and a 3-month follow-up for stroke recurrence as outcome. Profile groups of systolic blood pressure (SBP) were identified via an advanced functional clustering method, and the associations of the profile groups and conventional ABP parameters with stroke recurrence were examined in a Cox proportional hazards model.
resultsThree discrete profile groups (n=604, 781 and 611 in profiles 1, 2 and 3, respectively) in 24-hour ambulatory SBP were identified. Profile 1 resembled most to the normal diurnal blood pressure pattern; profile 2 also dropped at night, but climbed earlier and with higher morning surge; while profile 3 had sustained higher nocturnal SBP without significant nocturnal SBP decline. The incidence of stroke recurrence was 2.9%, 3.9% and 5.5% in profiles 1, 2 and 3, respectively. After adjustment for covariates, profile 3 was significantly associated with higher risk of stroke recurrence with profile 1 as reference (HR 1.76, 95% CI: 1.00 to 3.09), while no significant difference was observed between profiles 2 and 1 (HR 1.22, 95% CI: 0.66 to 2.25). None of conventional ABP parameters showed significant associations with the outcome.
conclusionsAmbulatory 24-hour SBP profile is associated with short-term stroke recurrence. Profiles of ABP may help improve identification of stroke recurrence by capturing the additive effects of individual ABP parameters.
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