ArticleThe Journal of neuroscience : the official journal of the Society for Neuroscience2021
Cross-Hemispheric Complementary Prefrontal Mechanisms during Task Switching under Perceptual Uncertainty.
Article in The Journal of neuroscience : the official journal of the Society for Neuroscience, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 2 of them syntheses that pooled it.
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Who cites it
14 citing papers in PubMed, 2 syntheses or guidelines pooled it, 33 citations in OpenAlex.
- Aging-related changes in cognitive flexibility: fMRI meta-analysis.Behavioral and brain functions : BBF · 2025Pooled it
- Mapping common and distinct brain correlates among cognitive flexibility tasks: concordant evidence from meta-analyses.Brain imaging and behavior · 2025Pooled it
- Task-Switch Related Reductions in Neural Distinctiveness in Children and Adults: Commonalities and Differences.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2025Article
- The unity/diversity framework of executive functions: behavioral and neural evidence in older adults.GeroScience · 2025Article
- Limitation of switching sensory information flow in flexible perceptual decision making.Nature communications · 2025Article
- Broadscale dampening of uncertainty adjustment in the aging brain.Nature communications · 2024Article
- Dyadic Similarity in Social Value Orientation Modulates Hyper-Brain Network Dynamics During Interpersonal Coordination: An fNIRS-Based Hyperscanning Study.Brain topography · 2024Article
- Basis of executive functions in fine-grained architecture of cortical and subcortical human brain networks.Cerebral cortex (New York, N.Y. : 1991) · 2024Article
- Cortical mechanisms of across-ear speech integration investigated using functional near-infrared spectroscopy (fNIRS).PloS one · 2024Article
- Cross-hemispheric recruitment during action planning with increasing task demand.Scientific reports · 2023Article
- The Stroop effect involves an excitatory-inhibitory fronto-cerebellar loop.Nature communications · 2023Article
- Perceptual Uncertainty Alternates Top-down and Bottom-up Fronto-Temporal Network Signaling during Response Inhibition.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2022Article
- The Higher, More Complicated: The Neural Mechanism of Hierarchical Task Switching on Prefrontal Cortex.Brain sciences · 2022Review
- Cognitive sequences in obsessive-compulsive disorder are supported by frontal cortex ramping activity.Imaging neuroscience (Cambridge, Mass.)Article
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Authors and funding
5 authors at 2 institutions in 1 country.
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No grant is acknowledged in the PubMed record.
Abstract
Flexible adaptation to changing environments is a representative executive control function implicated in the frontoparietal network that requires appropriate extraction of goal-relevant information through perception of the external environment. It remains unclear, however, how the flexibility is achieved under situations where goal-relevant information is uncertain. To address this issue, the current study examined neural mechanisms for task switching in which task-relevant information involved perceptual uncertainty. Twenty-eight human participants of both sexes alternated behavioral tasks in which they judged motion direction or color of visually presented colored dot stimuli that moved randomly. Task switching was associated with frontoparietal regions in the left hemisphere, and perception of ambiguous stimuli involved contralateral homologous frontoparietal regions. On the other hand, in stimulus-modality-dependent occipitotemporal regions, task coding information was increased during task switching. Effective connectivity analysis revealed that the frontal regions signaled toward the modality-dependent occipitotemporal regions when a relevant stimulus was more ambiguous, whereas the occipitotemporal regions signaled toward the frontal regions when the stimulus was more distinctive. These results suggest that complementary prefrontal mechanisms in the left and right hemispheres help to achieve a behavioral goal when the external environment involves perceptual uncertainty.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.