Observational studyBMJ open2021
Early Chronic Kidney Disease Care Programme delays kidney function deterioration in patients with stage I-IIIa chronic kidney disease: an observational cohort study in Taiwan.
Observational study in BMJ open, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
13 citing papers in PubMed, 1 synthesis or guideline pooled it, 20 citations in OpenAlex.
- Pooled it
- Typologies of Symptoms and Functions Among Patients With Chronic Kidney Disease and Population Characteristics: A Latent Profile Analysis.Nursing open · 2026Article
- Life's Essential 8 and Parkinson's Disease Risk: A Cross-Sectional Study Based on NHANES Data (2005-2018).Revista de neurologia · 2025Article
- "Kidney international reports · 2025Article
- Impact of early interruption from pay-for-performance program on progression and medical utilization for patients with early chronic kidney disease.International journal for quality in health care : journal of the International Society for Quality in Health Care · 2025Article
- Association between primary care physician-nephrologist collaboration and clinical outcomes in patients with stage 5 chronic kidney disease: a JOINT-KD cohort study.Journal of nephrology · 2025Article
- The association between deep vein thrombosis at admission and the time from injury to admission in hip fractures.BMC geriatrics · 2025Article
- Relationship between weight-to-waist index and post-stroke depression.World journal of psychiatry · 2025Article
- Association between dietary inflammatory index and Parkinson's disease from National Health and Nutrition Examination Survey (2003-2018): a cross-sectional study.Frontiers in neuroscience · 2023Article
- Nutrition and quality of life in chronic kidney disease patients: a practical approach for salt restriction.Kidney research and clinical practice · 2022Article
- Impact of collaboration between general practitioners and nephrologists on renal function: an experience in the Hitachi area.Clinical and experimental nephrology · 2022Article
- CKD Care Programs and Incident Kidney Failure: A Study of a National Disease Management Program in Taiwan.Kidney medicine · 2022Article
- Frailty, Health Literacy, and Self-Care in Patients with Chronic Kidney Disease in Taiwan.International journal of environmental research and public health · 2022Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivesTo investigate the effect of the Early Chronic Kidney Disease (CKD) Care Programme on CKD progression in patients with CKD stage I-IIIa.
designObservational cohort study.
settingTaipei Medical University Research Database from three affiliated hospitals.
participantsAdult non-pregnant patients with CKD stage I-IIIa from Taipei Medical University Research Database between 1 January 2012 and 31 August 2017 were recruited. These patients were divided into Early CKD Care Programme participants (case) and non-participants (control). The models were matched by age, sex, estimated glomerular filtration rate and CKD stage with 1:2 propensity score to reduce bias between two groups. OUTCOME MEASURES: The risks of CKD stage I-IIIa progression to IIIb between Early CKD Care Programme participants and non-participants.
resultsCompared with the control group, the case group demonstrated more comorbidities and higher proportions of hypertension, diabetes mellitus, gout, dyslipidaemia, heart disease and cerebrovascular disease, but had lower risk of progression to CKD stage IIIb before and (HR 0.72; 95% CI 0.61 to 0.85) and after (adjusted HR (aHR) 0.67; 95% CI 0.55 to 0.81) adjustments. Moreover, Kaplan-Meier analysis revealed the cumulative incidence of CKD stage IIIb was significantly lower in the case group than in the control group. Finally, the programme was an independent protective factor against progression to stage IIIb, especially in patients with CKD stage IIIa before (HR 0.72; 95% CI 0.61 to 0.85) and after (aHR 0.67; 95% CI 0.55 to 0.81) adjustments.
conclusionsThe Early CKD Care Programme is an independent protective factor against progression of early CKD.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.