Evidence map›Paper›PMID 33468488›Full record

ArticleAntimicrobial agents and chemotherapy2021

Adaptive Processes Change as Multiple Functions Evolve.

Portia M Mira, Bjørn Østman, Candace Guzman-Cole, Suzanne Sindi, Miriam Barlow

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Antimicrobial agents and chemotherapy, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.9field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 12 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Epistasis decreases with increasing antibiotic pressure but not temperature.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2023
    Article
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Portia M MiraDepartment of Ecology and Evolutionary Biology, University of California, Los Angeles, California, USA.
Bjørn ØstmanDepartment of Ecology and Evolutionary Biology, University of California, Los Angeles, California, USA.
Candace Guzman-ColeDepartment of Molecular and Cell Biology, School of Natural Sciences, University of California, Merced, California, USA.
Suzanne SindiDepartment of Applied Mathematics, School of Natural Sciences, University of California, Merced, California, USA.
Miriam BarlowDepartment of Molecular and Cell Biology, School of Natural Sciences, University of California, Merced, California, USA miriam.barlow@gmail.com.ORCID 0000-0002-7349-190X
University of California, Merced · USUniversity of California, Los Angeles · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Epistasis influences the gene-environment interactions that shape bacterial fitness through antibiotic exposure, which can ultimately affect the availability of certain resistance phenotypes to bacteria. The substitutions present within

Indexed as

beta-LactamasesEscherichia coliAnti-Bacterial Agentsbeta-Lactamase Inhibitorsbeta-Lactam ResistanceCephalosporinsMicrobial Sensitivity TestsAnti-Bacterial Agentsbeta-Lactamase Inhibitorsbeta-LactamasesCephalosporinsadaptive landscapebeta-lactamasedrug resistance evolution

Identifiers

PMID33468488
PMCPMC8097417
OpenAlexW3123006168

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.