Evidence map›Paper›PMID 33468485›Full record

ArticleAntimicrobial agents and chemotherapy2021

Limited Multidrug Resistance Efflux Pump Overexpression among Multidrug-Resistant Escherichia coli Strains of ST131.

Johannes Camp, Sabine Schuster, Martina Vavra, Tobias Schweigger, John W A Rossen, Sandra Reuter, Winfried V Kern

Open access · greenAbstract read
In one paragraph

Article in Antimicrobial agents and chemotherapy, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 1 pooled it
1.0field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 1 synthesis or guideline pooled it, 16 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Article
  6. Coexistence of blaAnnals of clinical microbiology and antimicrobials · 2024
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  7. The induced and intrinsic resistance ofMicrobiology spectrum · 2024
    Article
  8. Article
  9. Purine metabolism regulatesFrontiers in microbiology · 2023
    Article
  10. Article
  11. Article
  12. Review
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 3 countries.

Johannes CampDivision of Infectious Diseases, Department of Medicine II, Medical Centre and Faculty of Medicine, University of Freiburg, Freiburg, Germany johannes.camp@uniklinik-freiburg.de.ORCID 0000-0003-3914-4477
Sabine SchusterDivision of Infectious Diseases, Department of Medicine II, Medical Centre and Faculty of Medicine, University of Freiburg, Freiburg, Germany.ORCID 0000-0002-8817-6224
Martina VavraDivision of Infectious Diseases, Department of Medicine II, Medical Centre and Faculty of Medicine, University of Freiburg, Freiburg, Germany.
Tobias SchweiggerDivision of Infectious Diseases, Department of Medicine II, Medical Centre and Faculty of Medicine, University of Freiburg, Freiburg, Germany.
John W A RossenDepartment of Medical Microbiology and Infection Prevention, Faculty of Medical Sciences, University of Groningen, University Medical Center Groningen, Groningen, Netherlands.
Sandra ReuterInstitute for Infection Prevention and Hospital Epidemiology, Center for Microbiology, Virology and Hygiene, Medical Centre and Faculty of Medicine, University of Freiburg, Freiburg, Germany.
Winfried V KernDivision of Infectious Diseases, Department of Medicine II, Medical Centre and Faculty of Medicine, University of Freiburg, Freiburg, Germany.
University of Freiburg · DEUniversity Medical Center Groningen · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Gram-negative bacteria partly rely on efflux pumps to facilitate growth under stressful conditions and to increase resistance to a wide variety of commonly used drugs. In recent years,

Indexed as

Escherichia coliEscherichia coli ProteinsAnti-Bacterial AgentsDrug Resistance, Multiple, BacterialMicrobial Sensitivity TestsAnti-Bacterial AgentsEscherichia coli ProteinsAcrBE. colieffluxefflux pump inhibitorsST131

Identifiers

PMID33468485
PMCPMC8097430
OpenAlexW3125061614

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.