Evidence map›Paper›PMID 33468481›Full record

ArticleAntimicrobial agents and chemotherapy2021

Ethylzingerone, a Novel Compound with Antifungal Activity.

Tristan Rossignol, Sadri Znaidi, Murielle Chauvel, Rebecca Wesgate, Laurence Decourty, Florence Menard-Szczebara, Sylvie Cupferman, Maria Dalko-Sciba, Rosemary Barnes, Jean-Yves Maillard and 2 more

Open access · greenAbstract read
In one paragraph

Article in Antimicrobial agents and chemotherapy, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.4field-weighted citation impact, top 41% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 4 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 6 institutions in 3 countries.

Tristan Rossignol *Unité Biologie et Pathogénicité Fongiques, USC2019 INRA, Institut Pasteur, Paris, France.
Sadri Znaidi *Unité Biologie et Pathogénicité Fongiques, USC2019 INRA, Institut Pasteur, Paris, France.ORCID 0000-0001-9238-2218
Murielle ChauvelUnité Biologie et Pathogénicité Fongiques, USC2019 INRA, Institut Pasteur, Paris, France.
Rebecca WesgateCardiff School of Pharmacy and Pharmaceutical Sciences, Cardiff University, Cardiff, United Kingdom.
Laurence DecourtyUnité Génétique des Interactions Macromoléculaires, UMR3525 CNRS, Institut Pasteur, Paris, France.
Florence Menard-SzczebaraL'Oréal Research and Innovation, Aulnay sous Bois, France.
Sylvie CupfermanL'Oréal Research and Innovation, Aulnay sous Bois, France sylvie.cupferman@rd.loreal.com christophe.denfert@pasteur.fr.
Maria Dalko-ScibaL'Oréal Research and Innovation, Aulnay sous Bois, France.
Rosemary BarnesUniversity Hospital of Wales, Cardiff University, Cardiff, United Kingdom.
Jean-Yves MaillardUniversity Hospital of Wales, Cardiff University, Cardiff, United Kingdom.ORCID 0000-0002-8617-9288
Cosmin SaveanuUnité Génétique des Interactions Macromoléculaires, UMR3525 CNRS, Institut Pasteur, Paris, France.
Christophe d'EnfertUnité Biologie et Pathogénicité Fongiques, USC2019 INRA, Institut Pasteur, Paris, France sylvie.cupferman@rd.loreal.com christophe.denfert@pasteur.fr.ORCID 0000-0002-6235-3886
Institut Pasteur · FRL'Oréal (France) · FRCentre National de la Recherche Scientifique · FRUniversity Hospital of Wales · GBCardiff University · GBTunis University · TN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Preservatives increase the shelf life of cosmetic products by preventing growth of contaminating microbes, including bacteria and fungi. In recent years, the Scientific Committee on Consumer Safety (SCCS) has recommended the ban or restricted use of a number of preservatives due to safety concerns. Here, we characterize the antifungal activity of ethylzingerone (hydroxyethoxyphenyl butanone [HEPB]), an SCCS-approved new preservative for use in rinse-off, oral care, and leave-on cosmetic products. We show that HEPB significantly inhibits growth of

Indexed as

Antifungal AgentsCosmeticsCandida albicansSaccharomyces cerevisiaeAntifungal AgentsCosmeticsantifungalCandida albicanscosmeticsethylzingeroneHEPBhydroxyethoxyphenyl butanonemechanism of action

Identifiers

PMID33468481
PMCPMC8097443
OpenAlexW3124497786

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.