SynthesisBMJ open2021
Systems approach to health service design, delivery and improvement: a systematic review and meta-analysis.
Synthesis in BMJ open, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 53 papers, 4 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
53 citing papers in PubMed, 4 syntheses or guidelines pooled it.
- Enabling digital multifactorial risk assessment in primary care: an umbrella review and recommendations for design and implementation.BMJ health & care informatics · 2026Pooled it
- Patient and Staff Experience of Remote Patient Monitoring-What to Measure and How: Systematic Review.Journal of medical Internet research · 2024Pooled it
- Systems approaches to scaling up: a systematic review and narrative synthesis of evidence for physical activity and other behavioural non-communicable disease risk factors.The international journal of behavioral nutrition and physical activity · 2024Pooled it
- Purchasing high-cost medical devices and equipment in hospitals: a systematic review.BMJ open · 2022Pooled it
- Embedding onsite pharmacists in nursing home practice: qualitative findings from a pilot study.International journal of clinical pharmacy · 2026Article
- Facilitators of good consultations in primary health care clinics in Botswana: a qualitative study of patients' and doctors' views.BMC primary care · 2026Article
- Performance of Large Language Models in Answering Healthcare Delivery Questions: A Quantitative Cross-Sectional Study.Health science reports · 2026Article
- Complex intervention to improve empathy within maternity services: a mixed methods feasibility study with pilot evaluation.BMJ open quality · 2026Article
- Foundations of systems-based hematology: thematic analysis of expert interviews to guide curriculums and promote growth.Blood advances · 2026Article
- The breast cancer risk assessment pathway in England: a systems analysis of current challenges and ways to improve.British journal of cancer · 2026Article
- Challenges of community health nursing practice in the Primary Health Care network of Iran: a qualitative study.BMC health services research · 2026Article
- Visualisation of a complex healthcare system: mapping vascular and trauma surgery services in Ghana.BMC health services research · 2026Article
- A program theory for a continuing professional development program to enhance primary care nurses' mental health assessment practices.Frontiers in health services · 2026Article
- Article
- Cholesterol management in US adults with ASCVD in the Family Heart Database® during 2022-23: Current state of care and opportunities for improvement.American journal of preventive cardiology · 2025Article
- Advancing implementation of shared care for cancer survivors using a systems thinking approach (the SEAMLESS study).Journal of cancer survivorship : research and practice · 2025Article
- Social prescribing in primary care for people living with dementia: a qualitative exploration of different roles and services in England.BMC primary care · 2025Article
- The latent system factors that influence antimicrobial use and governance in healthcare: a scoping review of high-income health systems.EClinicalMedicine · 2025Review
- Access to communication support for community-dwelling people with dementia: A mixed methods study exploring local perspectives within the United Kingdom context.Age and ageing · 2025Article
- Bringing evolutionary cancer therapy to the clinic: a systems approach.NPJ systems biology and applications · 2025Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
15 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivesTo systematically review the evidence base for a systems approach to healthcare design, delivery or improvement.
designSystematic review with meta-analyses.
methodsIncluded were studies in any patients, in any healthcare setting where a systems approach was compared with usual care which reported quantitative results for any outcomes for both groups. We searched Medline, Embase, HMIC, Health Business Elite, Web of Science, Scopus, PsycINFO and CINAHL from inception to 28 May 2019 for relevant studies. These were screened, and data extracted independently and in duplicate. Study outcomes were stratified by study design and whether they reported patient and/or service outcomes. Meta-analysis was conducted with Revman software V.5.3 using ORs-heterogeneity was assessed using I
resultsOf 11 405 records 35 studies were included, of which 28 (80%) were before-and-after design only, five were both before-and-after and concurrent design, and two were randomised controlled trials (RCTs). There was heterogeneity of interventions and wide variation in reported outcome types. Almost all results showed health improvement where systems approaches were used. Study quality varied widely. Exploratory meta-analysis of these suggested favourable effects on both patient outcomes (n=14, OR=0.52 (95% CI 0.38 to 0.71) I
conclusionsThis study suggests that a systems approaches to healthcare design and delivery results in a statistically significant improvement to both patient and service outcomes. However, better quality studies, particularly RCTs are needed.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.