Evidence map›Paper›PMID 33468357›Full record

ArticleUltrasound in medicine & biology2021

Non-invasive Assessment of Liver Fat in ob/ob Mice Using Ultrasound-Induced Thermal Strain Imaging and Its Correlation with Hepatic Triglyceride Content.

Waqas B Khalid, Nadim Farhat, Linda Lavery, Josh Jarnagin, James P Delany, Kang Kim

Erratum issuedOpen access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Ultrasound in medicine & biology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact, top 99% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 2 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Waqas B KhalidDepartment of Bioengineering, University of Pittsburgh School of Engineering, Pittsburgh, Pennsylvania, USA.
Nadim FarhatDepartment of Bioengineering, University of Pittsburgh School of Engineering, Pittsburgh, Pennsylvania, USA.
Linda LaveryCenter for Ultrasound Molecular Imaging and Therapeutics, Department of Medicine, University of Pittsburgh School of Medicine, Heart and Vascular Institute, University of Pittsburgh Medical Center.
Josh JarnaginDepartment of Medicine, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA.
James P DelanyDepartment of Medicine, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA.
Kang KimDepartment of Bioengineering, University of Pittsburgh School of Engineering, Pittsburgh, Pennsylvania, USA; Center for Ultrasound Molecular Imaging and Therapeutics, Department of Medicine, University of Pittsburgh School of Medicine, Heart and Vascular Institute, University of Pittsburgh Medical Center; Department of Medicine, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA; Department of Mechanical Engineering and Materials Science, University of Pittsburgh School of Engineering, Pittsburgh, Pennsylvania, USA; McGowan Institute for Regenerative Medicine, University of Pittsburgh and University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania, USA. Electronic address: kangkim@upmc.edu.
University of Pittsburgh · USMcGowan Institute for Regenerative Medicine · USUniversity of Pittsburgh Medical Center · US

Funding

High-resolution ultrasound in-vivo animal imaging system-Vevo2100S10RR027383 · NCRR · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI KIM, KANG · 2010 to 2010
$498k
Noninvasive fat quantification of liver using ultrasound thermal strain imagingR21EB016907 · NIBIB · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI KIM, KANG · 2014 to 2015
$423k
NCRR NIH HHS S10 RR027383NIBIB NIH HHS R21 EB016907
6 · The paper itself

Abstract

Non-alcoholic fatty liver disease is the accumulation of triglycerides in liver. In its malignant form, it can proceed to steatohepatitis, fibrosis, cirrhosis, cancer and ultimately liver impairment, leading to liver transplantation. In a previous study, ultrasound-induced thermal strain imaging (US-TSI) was used to distinguish between excised fatty livers from obese mice and non-fatty livers from control mice. In this study, US-TSI was used to quantify lipid composition of fatty livers in ob/ob mice (n = 28) at various steatosis stages. A strong correlation coefficient was observed (R

Indexed as

Adipose TissueAnimalsMiceMice, ObeseNon-alcoholic Fatty Liver DiseaseSignal Processing, Computer-AssistedTriglyceridesUltrasonographyTriglyceridesHepatic triglyceride contentNon-alcoholic fatty liver diseaseObese mouseUltrasound-induced thermal strain imaging

Identifiers

PMID33468357
PMCPMC7936391
OpenAlexW3121328427

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.