ArticleTrials2021
In silico imaging clinical trials: cheaper, faster, better, safer, and more scalable.
Article in Trials, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
28 citing papers in PubMed.
- Synthetic-to-Clinical Ensemble Learning for Volumetric Breast Tumor Segmentation in Digital Breast Tomosynthesis Under Limited Annotated Data.Diagnostics (Basel, Switzerland) · 2026Article
- In Silico Digital Breast Tomosynthesis Dataset for the Comparative Analysis of Deep Learning Models in Tumor Segmentation.Journal of imaging informatics in medicine · 2026Article
- Labeled Numerical Phantom of Abdominal Wall for Wave-Physics-Based Ultrasound Imaging: Applications to Image Reconstruction.IEEE transactions on ultrasonics · 2026Article
- Survey of Deep Learning and Physics-Based Approaches in Computational Wave Imaging.Proceedings of the IEEE. Institute of Electrical and Electronics Engineers · 2025Article
- Radiomics Quality Score 2.0: towards radiomics readiness levels and clinical translation for personalized medicine.Nature reviews. Clinical oncology · 2025Review
- Sensitivity analysis of key CT simulation parameters and their impact on quality of virtual images.Medical physics · 2025Article
- Multiscale modeling of drug-induced liver injury from organ to lobule.NPJ digital medicine · 2025Article
- An open source statistical web application for validation and analysis of virtual cohorts.Scientific reports · 2025Article
- Toward Uncertainty-Aware Hemolysis Modeling: A Universal Approach to Address Experimental Variance.International journal for numerical methods in biomedical engineering · 2025Article
- A Review of the Applications, Benefits, and Challenges of Generative AI for Sustainable Toxicology.Current research in toxicology · 2025Review
- ISIT-GEN: An in silico imaging trial to assess the inter-scanner generalizability of CTLESS for myocardial perfusion SPECT on defect-detection task.Proceedings of SPIE--the International Society for Optical Engineering · 2025Article
- Article
- The emerging challenge ofClinical microbiology reviews · 2024Review
- Toward widespread use of virtual trials in medical imaging innovation and regulatory science.Medical physics · 2024Review
- A virtual scalable model of the Hepatic Lobule for acetaminophen hepatotoxicity prediction.NPJ digital medicine · 2024Article
- Monte Carlo methods for medical imaging research.Biomedical engineering letters · 2024Review
- Evaluating the Therapeutic Potential of Curcumin and Synthetic Derivatives: A Computational Approach to Anti-Obesity Treatments.International journal of molecular sciences · 2024Article
- Synthetic data in radiological imaging: current state and future outlook.BJR artificial intelligence · 2024Review
- Toward trustworthy medical deviceFrontiers in medicine · 2024Article
- Ideal Observer Computation by Use of Markov-Chain Monte Carlo With Generative Adversarial Networks.IEEE transactions on medical imaging · 2023Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Imaging clinical trials can be burdensome and often delay patient access to novel, high-quality medical devices. Tools for in silico imaging trials have significantly improved in sophistication and availability. Here, I describe some of the principal advantages of in silico imaging trials and enumerate five lessons learned during the design and execution of the first all-in silico virtual imaging clinical trial for regulatory evaluation (the VICTRE study).
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.