Evidence map›Paper›PMID 33468133›Full record

ArticleHarm reduction journal2021

Individual and structural correlates of willingness for intravenous buprenorphine treatment among people who inject sublingual buprenorphine in France.

Salim Mezaache, Patrizia Carrieri, Laélia Briand-Madrid, Virginie Laporte, Alain Morel, Daniela Rojas Castro, Perrine Roux

Erratum issuedOpen access · goldAbstract read
In one paragraph

Article in Harm reduction journal, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
1.6field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 10 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Salim MezaacheINSERM, IRD, SESSTIM, Sciences Économiques & Sociales de La Santé & Traitement de L'information Médicale, Aix-Marseille Univ, Marseille, France. salim.mezaache@inserm.fr.ORCID 0000-0002-8396-3667
Patrizia CarrieriINSERM, IRD, SESSTIM, Sciences Économiques & Sociales de La Santé & Traitement de L'information Médicale, Aix-Marseille Univ, Marseille, France.
Laélia Briand-MadridINSERM, IRD, SESSTIM, Sciences Économiques & Sociales de La Santé & Traitement de L'information Médicale, Aix-Marseille Univ, Marseille, France.
Virginie LaporteAides, Pantin, France.
Alain MorelAssociation Oppelia, Paris, France.
Daniela Rojas CastroINSERM, IRD, SESSTIM, Sciences Économiques & Sociales de La Santé & Traitement de L'information Médicale, Aix-Marseille Univ, Marseille, France.
Perrine RouxINSERM, IRD, SESSTIM, Sciences Économiques & Sociales de La Santé & Traitement de L'information Médicale, Aix-Marseille Univ, Marseille, France.
Inserm · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundSome people do not benefit from oral administration of opioid agonist treatment, and an intravenous (IV) formulation may be more suitable. Our objective was to evaluate the willingness of people who regularly inject sublingual buprenorphine to receive IV buprenorphine as a prescribed treatment, and to examine related correlates.

methodsWe performed a secondary analysis of data from the cross-sectional study PrebupIV, conducted in France in 2015 among 557 people who inject opioids. The study comprised questionnaires completed either face to face or online and community-based workshops. We only included participants who reported buprenorphine as their main injected drug (n = 209). Willingness to receive IV buprenorphine treatment was measured on a scale from 0 to 10. Ordinal logistic regression identified correlates of willingness. Artworks and testimonies from participants in the workshops were also used to illustrate correlates of willingness.

resultsAmong the 209 participants, the mean score (SD) for willingness to receive IV buprenorphine was 8.0 (2.8). Multivariate analysis showed that participants who reported using non-prescribed buprenorphine (AOR = 4.82, p = 0.019), a higher daily dosage of buprenorphine (AOR (for 1 mg) = 1.05, p = 0.043), and a higher number of complications due to injection (AOR = 2.28, p = 0.037), were more willing to receive IV buprenorphine treatment.

conclusionsWillingness to initiate IV buprenorphine treatment was high among people who regularly inject sublingual buprenorphine. A prescribed IV formulation could attract and retain more people into care and reduce harms associated with the injection of buprenorphine tablets.

Indexed as

BuprenorphineOpioid-Related DisordersSubstance Abuse, IntravenousAdministration, OralAnalgesics, OpioidCross-Sectional StudiesHumansSurveys and QuestionnairesAnalgesics, OpioidBuprenorphineHarm reductionIntravenous substance abuseOpiate substitution treatmentOpioid-related disorders

Identifiers

PMID33468133
PMCPMC7814710
OpenAlexW3125092180

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.