ArticleBMC musculoskeletal disorders2021
Is there a correlation between upper lumbar disc herniation and multifidus muscle degeneration? A retrospective study of MRI morphology.
Article in BMC musculoskeletal disorders, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.
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Who cites it
23 citing papers in PubMed.
- The effects of Pilates on pain, functionality, quality of life, flexibility and endurance in lumbar disc herniation.Journal of comparative effectiveness research · 2023Trial
- Diagnostic Perspectives on the Relationship Between Paraspinal Muscles and Bone Mineral Density: A Narrative Review.Diagnostics (Basel, Switzerland) · 2026Review
- Article
- Full-Endoscopic Surgery for Lumbar Disc Herniation: Comparative Outcomes and Risk Factors Between Lumbar Levels-The EndoLEVEL Study.International journal of spine surgery · 2026Article
- Development and validation of a CT-based predictive model for new vertebral compression fractures: the role of vertebral CT attenuation and paraspinal muscle.Frontiers in medicine · 2026Article
- Based on the mechanism of degeneration of the small joint - muscle - intervertebral disc complex and early intervention.Annals of medicine and surgery (2012) · 2025Article
- Endoscopic Surgical Strategy for Upper Lumbar Disc Herniation With Spinal Canal Stenosis: A Technical Note.Cureus · 2025Article
- Research progress on sarcopenia in the musculoskeletal system.Bone research · 2025Review
- Impact of Paraspinal Sarcopenia on Clinical Outcomes in Intervertebral Disc Degeneration Patients Following Percutaneous Transforaminal Endoscopic Lumbar Discectomy.Orthopaedic surgery · 2025Article
- Percutaneous transforaminal endoscopic discectomy for Upper Lumbar Disc Herniation versus lower lumbar disc herniation: clinical outcomes and technical consideration.BMC musculoskeletal disorders · 2024Article
- Clinical efficacy and complications of MIS-TLIF and TLIF in the treatment of upper lumbar disc herniation: a comparative study.Journal of orthopaedic surgery and research · 2024Article
- Association of Preoperative Osteoporotic Vertebral Compression Fractures with Muscle Atrophy in Lumbar Spinal Stenosis: A Retrospective Cohort Study.Progress in rehabilitation medicine · 2024Article
- Advances in the interaction between lumbar intervertebral disc degeneration and fat infiltration of paraspinal muscles: critical summarization, classification, and perspectives.Frontiers in endocrinology · 2024Review
- The effect of lumbar multifidus muscle degeneration on upper lumbar disc herniation.Frontiers in surgery · 2024Article
- The effect of aspirin on lumbar degeneration: an imaging-based study.Frontiers in surgery · 2024Article
- Biomechanical effect of proximal multifidus injury on adjacent segments during posterior lumbar interbody fusion: a finite element study.BMC musculoskeletal disorders · 2023Article
- The association between morphological characteristics of paraspinal muscle and spinal disorders.Annals of medicine · 2023Review
- Forecast of pain degree of lumbar disc herniation based on back propagation neural network.Open life sciences · 2023Article
- Total Resorption of a Chronic L4-L5 Disc Extrusion After Application of the Atlasprofilax Method: A Case Report.The American journal of case reports · 2022Article
- Advances in research on fat infiltration and lumbar intervertebral disc degeneration.Frontiers in endocrinology · 2022Review
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Authors and funding
11 authors.
Funding
Abstract
backgroundThe purpose of the study is to investigate the correlation between upper lumbar disc herniation (ULDH) and multifidus muscle degeneration via the comparison of width, the cross-sectional area and degree of fatty infiltration of the lumbar multifidus muscle.
methodsUsing the axial T2-weighted images of magnetic resonance imaging as an assessment tool, we retrospectively investigated 132 patients with ULDH and 132 healthy individuals. The total muscle cross-sectional area (TMCSA) and the pure muscle cross-sectional area (PMCSA) of the multifidus muscle at the L1/2, L2/3, and L3/4 intervertebral disc levels were measured respectively, and in the meantime, the average multifidus muscle width (AMMW) and degree of fatty infiltration of bilateral multifidus muscle were evaluated. The resulting data were analyzed to determine the presence/absence of statistical significance between the study and control groups. Multivariate logistical regression analyses were used to evaluate the correlation between ULDH and multifidus degeneration.
resultsThe results of the analysis of the two groups showed that there were statistically significant differences (p < 0.05) between TMCSA, PMCSA, AMMW and degree of fatty infiltration. The multivariate logistic regression analysis indicated that the TMCSA, PMCSA, AMMW and the degree of fatty infiltration of multifidus muscle were correlated with ULDH, and the differences were statistically significant (P < 0.05).
conclusionsA correlation could exist between multifidus muscles degeneration and ULDH, that may be a process of mutual influence and interaction. Lumbar muscle strengthening training could prevent and improve muscle atrophy and degeneration.
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