Evidence map›Paper›PMID 33468099›Full record

Observational studyBMC neurology2021

Neurocritical care complications and interventions influence the outcome in aneurysmal subarachnoid hemorrhage.

Alexander Hammer, Frank Erbguth, Matthias Hohenhaus, Christian M Hammer, Hannes Lücking, Markus Gesslein, Monika Killer-Oberpfalzer, Hans-Herbert Steiner, Hendrik Janssen

Open access · goldAbstract readObservational Study
In one paragraph

Observational study in BMC neurology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.1field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 11 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 2 countries.

Alexander HammerDepartment of Neurosurgery, Paracelsus Medical University, Breslauer Straße 201, 90471, Bavaria, Nuremberg, Germany. alexander.hammer@klinikum-nuernberg.de.
Frank ErbguthDepartment of Neurology, Paracelsus Medical University, Breslauer Str. 201, 90471, Bavaria, Nuremberg, Germany.
Matthias HohenhausDepartment of Anaesthesiology, Paracelsus Medical University, Breslauer Str. 201, 90471, Bavaria, Nuremberg, Germany.
Christian M HammerDepartment of Anatomy 2, University of Erlangen-Nuremberg, Universitätsstraße 19, 91054, Bavaria, Erlangen, Germany.
Hannes LückingDepartment of Neuroradiology, University of Erlangen-Nürnberg, Schwabachanlage 6, 91054, Erlangen, Germany.
Markus GessleinDepartment of Orthopaedics and Traumatology, Paracelsus Medical University, Breslauer Str. 201, 90471, Bavaria, Nuremberg, Germany.
Monika Killer-OberpfalzerNeurology/Research Institute of Neurointervention, Paracelsus Medical University, Ignaz Harrer Str. 79, Salzburg, Austria.
Hans-Herbert SteinerDepartment of Neurosurgery, Paracelsus Medical University, Breslauer Straße 201, 90471, Bavaria, Nuremberg, Germany.
Hendrik JanssenDepartment of Neuroradiology, Ingolstadt General Hospital, Krumenauerstraße 25, 85049, Bavaria, Ingolstadt, Germany.
Paracelsus Medizinische Privatuniversität · DEFriedrich-Alexander-Universität Erlangen-Nürnberg · DEKlinikum Ingolstadt · DEParacelsus Medical University · AT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThis observational study was performed to show the impact of complications and interventions during neurocritical care on the outcome after aneurysmal subarachnoid hemorrhage (SAH).

methodsWe analyzed 203 cases treated for ruptured intracranial aneurysms, which were classified regarding clinical outcome after one year according to the modified Rankin Scale (mRS). We reviewed the data with reference to the occurrence of typical complications and interventions in neurocritical care units.

resultsDecompressive craniectomy (odds ratio 21.77 / 6.17 ; p < 0.0001 / p = 0.013), sepsis (odds ratio 14.67 / 6.08 ; p = 0.037 / 0.033) and hydrocephalus (odds ratio 3.71 / 6.46 ; p = 0.010 / 0.00095) were significant predictors for poor outcome and death after one year beside "World Federation of Neurosurgical Societies" (WFNS) grade (odds ratio 3.86 / 4.67 ; p < 0.0001 / p < 0.0001) and age (odds ratio 1.06 / 1.10 ; p = 0.0030 / p < 0.0001) in our multivariate analysis (binary logistic regression model).

conclusionsIn summary, decompressive craniectomy, sepsis and hydrocephalus significantly influence the outcome and occurrence of death after aneurysmal SAH.

Indexed as

Treatment OutcomeAgedCraniotomyCritical CareDecompression, SurgicalFemaleHumansHydrocephalusMaleMiddle AgedSepsisSubarachnoid HemorrhageDecompressive craniectomyIntracranial aneurysmNeurocritical careOutcomeSubarachnoid hemorrhageVascular disorders

Identifiers

PMID33468099
PMCPMC7814559
OpenAlexW3124311288

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.