Evidence map›Paper›PMID 33468073›Full record

ArticleBMC infectious diseases2021

Phenotype, molecular characterisation and risk factors for postoperative meningitis caused by ESBL-producing-Enterobacteriaceae: a six years multi-Centre comparative cohort study.

Guanghui Zheng, Yanfei Cao, Chunhong Liu, Lingye Qian, Yumeng Cai, Miaomiao Cui, Huiting Sun, Lv Hong, Jun Yuan, Lina Zhang and 1 more

Open access · goldAbstract readComparative StudyMulticenter Study
In one paragraph

Article in BMC infectious diseases, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
0.7field-weighted citation impact, top 40% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 11 citations in OpenAlex.

  1. Article
  2. Postoperative meningitis due to carbapenemase-producingSurgical neurology international · 2025
    Article
  3. Guidelines for Antibiotics Prescription in Critically Ill Patients.Indian journal of critical care medicine : peer-reviewed, official publication of Indian Society of Critical Care Medicine · 2024
    Article
  4. Epidemiology and antimicrobial resistance patterns of bacterial meningitis among hospitalized patients at a tertiary care hospital in Saudi Arabia: a six-year retrospective study.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2024
    Article
  5. Article
  6. Article
  7. Article
  8. Review
  9. Review
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 5 institutions in 1 country.

Guanghui Zheng *Department of Clinical Diagnosis, Laboratory of Beijing Tiantan Hospital and Capital Medical University, NO. 119 Nansihuan West road, Fengtai district, Beijing, China.
Yanfei Cao *Daqing Oilfield General Hospital Clinical Laboratory, No. 9 Zhongkang Street, Saltu District, Daqing, China.
Chunhong Liu *Department of Clinical Diagnosis, Laboratory of Sanbo Brain Hospital and Capital Medical University, NO.50 Yikesong Road, Haidian District, Beijing, China.
Lingye QianDepartment of Clinical Diagnosis, Laboratory of Beijing Tiantan Hospital and Capital Medical University, NO. 119 Nansihuan West road, Fengtai district, Beijing, China.
Yumeng CaiDepartment of Clinical Diagnosis, Laboratory of Beijing Tiantan Hospital and Capital Medical University, NO. 119 Nansihuan West road, Fengtai district, Beijing, China.
Miaomiao CuiDepartment of Clinical Diagnosis, Laboratory of the Second People's Hospital of Guiyang, Guiyang, China.
Huiting SunDepartment of Clinical Diagnosis, Laboratory of Sanbo Brain Hospital and Capital Medical University, NO.50 Yikesong Road, Haidian District, Beijing, China.
Lv HongDepartment of Clinical Diagnosis, Laboratory of Beijing Tiantan Hospital and Capital Medical University, NO. 119 Nansihuan West road, Fengtai district, Beijing, China.
Jun YuanDepartment of Clinical Diagnosis, Laboratory of the Second People's Hospital of Guiyang, Guiyang, China. junyuan99430@163.com.
Lina ZhangDaqing Oilfield General Hospital Clinical Laboratory, No. 9 Zhongkang Street, Saltu District, Daqing, China. zhanglina9@126.com.
Guojun ZhangDepartment of Clinical Diagnosis, Laboratory of Beijing Tiantan Hospital and Capital Medical University, NO. 119 Nansihuan West road, Fengtai district, Beijing, China. zgjlunwen@sina.com.
Capital Medical University · CNBeijing Tian Tan Hospital · CNDaqing Oilfield General Hospital · CNThe First People's Hospital of Guiyang · CNXian Yang Central Hospital · CN

Funding

Beijing Municipal Administration of Hospitals Clinical Medicine Development of Special Funding Support QML20180502
6 · The paper itself

Abstract

backgroundTo determine the phenotype, molecular characterisation and risk factors of postoperative meningitis induced by Extended-spectrum β-lactamase (ESBL)-producing Enterobacteriaceae (EPE) in China.

methodsWe performed a multi-centre comparative cohort study of postoperative meningitis patients infected with Enterobacteriaceae in 4 neurosurgical centres in China from January 2014 to December 2019. Phenotype and molecular characteristics of the isolates were reviewed and tested, and independent risk factors of the EPE meningitis were evaluated by binary logistic regression.

resultsIn total, 220 Enterobacteriaceae include 78 EPE were available in this study. 85.6% (67/78) ESBL-related genes were tested, and bla

conclusionsTo the best of our knowledge, this is the largest series focusing on risk factors of EPE meningitis which has been conducted in China. Craniotomy and malignancy were independent risk factors for EPE meningitis. The risk factors identified may be further utilized in clinical practice and research to avoid and reduce the mortality in future.

Indexed as

Adultbeta-LactamasesChinaCohort StudiesEnterobacteriaceaeEnterobacteriaceae InfectionsFemaleHumansMaleMeningitis, BacterialPhenotypePolymerase Chain ReactionPostoperative ComplicationsRetrospective StudiesRisk Factorsbeta-LactamasesEnterobacteriaceaeESBLMeningitisMolecular characterisationRisk factor

Identifiers

PMID33468073
PMCPMC7816392
OpenAlexW3123576973

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.