ArticleBMC plant biology2021
Exogenous application of xanthine and uric acid and nucleobase-ascorbate transporter MdNAT7 expression regulate salinity tolerance in apple.
Article in BMC plant biology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
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Who cites it
13 citing papers in PubMed.
- Long-Term Salt Exposure Reprograms the Nicotiana tabacum BY-2 Suspension Proteome and Metabolome Toward Stabilization of the Core Metabolic Pathways, Protein Turnover Machinery Modifications, and Protective Metabolome Adjustments.Plant, cell & environment · 2026Article
- Metabolomic Profiling Identifies Key Metabolites and Defense Pathways inInternational journal of molecular sciences · 2025Article
- Dual defense: melatonin simultaneously mitigates cadmium toxicity and southern blight in peanut.Frontiers in plant science · 2025Article
- Effects of Nitrogen Deficiency on the Photosynthesis, ChlorophyllInternational journal of molecular sciences · 2024Article
- Integrated transcriptomics, metabolomics and physiological analyses reveal differential response mechanisms of wheat to cadmium and/or salinity stress.Frontiers in plant science · 2024Article
- Colonization of root endophytic fungusFrontiers in microbiology · 2024Article
- Unique Features of the mInternational journal of molecular sciences · 2023Article
- An miR156-regulated nucleobase-ascorbate transporter 2 confers cadmium tolerance via enhanced anti-oxidative capacity in barley.Journal of advanced research · 2023Article
- Molecular and physiological mechanisms of tea (Camellia sinensis (L.) O. Kuntze) leaf and root in response to nitrogen deficiency.BMC genomics · 2023Article
- Identification of southern corn rust resistance QTNs in Chinese summer maize germplasm via multi-locus GWAS and post-GWAS analysis.Frontiers in plant science · 2023Article
- Root Breeding in the Post-Genomics Era: From Concept to Practice in Apple.Plants (Basel, Switzerland) · 2022Review
- Methylome and transcriptome analyses of three different degrees of albinism in apple seedlings.BMC genomics · 2022Article
- Integrated Analysis of Physiological, mRNA Sequencing, and miRNA Sequencing Data Reveals a Specific Mechanism for the Response to Continuous Cropping Obstacles inFrontiers in plant science · 2022Article
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Authors and funding
8 authors.
Funding
Abstract
backgroundSoil salinity is a critical threat to global agriculture. In plants, the accumulation of xanthine activates xanthine dehydrogenase (XDH), which catalyses the oxidation/conversion of xanthine to uric acid to remove excess reactive oxygen species (ROS). The nucleobase-ascorbate transporter (NAT) family is also known as the nucleobase-cation symporter (NCS) or AzgA-like family. NAT is known to transport xanthine and uric acid in plants. The expression of MdNAT is influenced by salinity stress in apple.
resultsIn this study, we discovered that exogenous application of xanthine and uric acid enhanced the resistance of apple plants to salinity stress. In addition, MdNAT7 overexpression transgenic apple plants showed enhanced xanthine and uric acid concentrations and improved tolerance to salinity stress compared with nontransgenic plants, while opposite phenotypes were observed for MdNAT7 RNAi plants. These differences were probably due to the enhancement or impairment of ROS scavenging and ion homeostasis abilities.
conclusionOur results demonstrate that xanthine and uric acid have potential uses in salt stress alleviation, and MdNAT7 can be utilized as a candidate gene to engineer resistance to salt stress in plants.
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