Evidence map›Paper›PMID 33467913›Full record

Trial reportExperimental biology and medicine (Maywood, N.J.)2021

Retinol-binding protein, retinol, and modified-relative-dose response in Ugandan children aged 12-23 months and their non-pregnant caregivers.

Ralph D Whitehead, Nicole D Ford, Carine Mapango, Laird J Ruth, Ming Zhang, Rosemary L Schleicher, Sarah Ngalombi, Siti Halati, Martin Ahimbisibwe, Abdelrahman Lubowa and 3 more

Open access · greenAbstract readClinical TrialMulticenter Study
In one paragraph

Trial report in Experimental biology and medicine (Maywood, N.J.), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.4field-weighted citation impact, top 42% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 5 citations in OpenAlex.

  1. Vitamin A biomarkers were associated withThe British journal of nutrition · 2024
    Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 6 institutions in 2 countries.

Ralph D WhiteheadDivision of Nutrition, Physical Activity, and Obesity, National Center for Chronic Disease Prevention and Health Promotion, 1242Centers for Disease Control and Prevention, Atlanta, GA 30341, USA.ORCID 0000-0002-0192-5115
Nicole D FordMcKing Consulting Corporation, Atlanta, GA 30341, USA.ORCID 0000-0002-6463-5094
Carine MapangoDivision of Laboratory Sciences, National Center for Environmental Health, Centers for Disease Control and Prevention, Atlanta, GA 30341, USA.
Laird J RuthMcKing Consulting Corporation, Atlanta, GA 30341, USA.
Ming ZhangDivision of Laboratory Sciences, National Center for Environmental Health, Centers for Disease Control and Prevention, Atlanta, GA 30341, USA.
Rosemary L SchleicherDivision of Laboratory Sciences, National Center for Environmental Health, Centers for Disease Control and Prevention, Atlanta, GA 30341, USA.
Sarah NgalombiMinistry of Health, Kampala, 10101, Uganda.
Siti HalatiWorld Food Programme, Kampala, 10101, Uganda.
Martin AhimbisibweWorld Food Programme, Kampala, 10101, Uganda.
Abdelrahman LubowaSchool of Food Technology, Nutrition and Bioengineering, Makerere University, Kampala, 10101, Uganda.
Jesse SheftelDepartment of Nutritional Sciences, University of Wisconsin-Madison, Madison, WI 53706, USA.ORCID 0000-0002-0875-5454
Sherry A TanumihardjoDepartment of Nutritional Sciences, University of Wisconsin-Madison, Madison, WI 53706, USA.ORCID 0000-0002-7022-1760
Maria Elena D JefferdsDivision of Nutrition, Physical Activity, and Obesity, National Center for Chronic Disease Prevention and Health Promotion, 1242Centers for Disease Control and Prevention, Atlanta, GA 30341, USA.ORCID 0000-0002-2652-4502
Centers for Disease Control and Prevention · USMcKing Consulting (United States) · USUniversity of Wisconsin–Madison · USWorld Health Organization - Uganda · UGMakerere University · UGMinistry of Health · UG

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Retinol-binding protein (RBP), retinol, and modified-relative-dose response (MRDR) are used to assess vitamin A status. We describe vitamin A status in Ugandan children and women using dried blood spot (DBS) RBP, serum RBP, plasma retinol, and MRDR and compare DBS-RBP, serum RBP, and plasma retinol. Blood was collected from 39 children aged 12-23 months and 28 non-pregnant mothers aged 15-49 years as a subsample from a survey in Amuria district, Uganda, in 2016. DBS RBP was assessed using a commercial enzyme immunoassay kit, serum RBP using an in-house sandwich enzyme-linked immunosorbent assay, and plasma retinol/MRDR test using high-performance liquid chromatography. We examined (a) median concentration or value (Q1, Q3); (b)

Indexed as

CaregiversAdolescentAdultFemaleHumansInfantMaleMiddle AgedRetinol-Binding ProteinsUgandaVitamin ARetinol-Binding ProteinsVitamin Adried blood spotsmodified-relative-dose responseRetinolretinol-binding proteinserumvitamin A

Identifiers

PMID33467913
PMCPMC8024505
OpenAlexW3121997482

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.