Evidence map›Paper›PMID 33467738›Full record

ArticleCells2021

The Predictive Value of miR-16, -29a and -134 for Early Identification of Gestational Diabetes: A Nested Analysis of the DALI Cohort.

Anja Elaine Sørensen, Mireille N M van Poppel, Gernot Desoye, Peter Damm, David Simmons, Dorte Møller Jensen, Louise Torp Dalgaard, The DALI Core Investigator Group

Open access · goldAbstract read
In one paragraph

Article in Cells, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
33citing papers in PubMed, 2 pooled it
6.1field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

33 citing papers in PubMed, 2 syntheses or guidelines pooled it, 50 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 5 institutions in 3 countries.

Anja Elaine SørensenDepartment of Science and Environment, Roskilde University, 4000 Roskilde, Denmark.ORCID 0000-0001-7557-5376
Mireille N M van PoppelInstitute of Human Movement Science, Sport and Health, University of Graz, 8010 Graz, Austria.ORCID 0000-0001-5694-4324
Gernot DesoyeDepartment of Obstetrics and Gynecology, Medizinische Universitaet Graz, 8036 Graz, Austria.ORCID 0000-0002-5715-3230
Peter DammCenter for Pregnant Women with Diabetes, Department of Obstetrics, Rigshospitalet, Department of Clinical Medicine, University of Copenhagen, 2100 Copenhagen, Denmark.ORCID 0000-0002-2067-5246
David SimmonsMacarthur Clinical School, Western Sydney University, Sydney 2560, Australia.ORCID 0000-0003-0560-0761
Dorte Møller JensenSteno Diabetes Center Odense, Department of Gynecology and Obstetrics, Odense University Hospital, 5000 Odense, Denmark.
Louise Torp DalgaardDepartment of Science and Environment, Roskilde University, 4000 Roskilde, Denmark.ORCID 0000-0002-3598-2775
The DALI Core Investigator Group
Roskilde University · DKUniversity of Copenhagen · DKSteno Diabetes Centers · DKUniversity of Graz · ATWestern Sydney University · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Early identification of gestational diabetes mellitus (GDM) aims to reduce the risk of adverse maternal and perinatal outcomes. Currently, no circulating biomarker has proven clinically useful for accurate prediction of GDM. In this study, we tested if a panel of small non-coding circulating RNAs could improve early prediction of GDM. We performed a nested case-control study of participants from the European multicenter 'Vitamin D and lifestyle intervention for GDM prevention (DALI)' trial using serum samples from obese pregnant women (BMI ≥ 29 kg/m

Indexed as

AdultAnthropometryArea Under CurveBiomarkersCase-Control StudiesDiabetes, GestationalFemaleHumansLife StyleMicroRNAsObesityPredictive Value of TestsPregnancyReal-Time Polymerase Chain ReactionRisk AssessmentRNA, Small UntranslatedBiomarkersMicroRNAsMIRN134 microRNA, humanMIRN16 microRNA, humanMIRN29a microRNA, humanRNA, Small Untranslatedcirculating microRNAGestational diabetes mellitusmicroRNAsmiR-122-5pmiR-134-5pmiR-16-5pmiR-29a-3pobesitypredictive biomarkerpregnancyrandomized control trialserum

Identifiers

PMID33467738
PMCPMC7830355
OpenAlexW3119696809

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.