ReviewMaterials (Basel, Switzerland)2021
The Antibacterial Effects of Resin-Based Dental Sealants: A Systematic Review of In Vitro Studies.
Review in Materials (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
12 citing papers in PubMed, 22 citations in OpenAlex.
- Article
- Antibacterial properties of bioengineered silver nanoparticles from Pastinaca sativa against Enterococcus faecalis biofilms in endodontic therapy.Scientific reports · 2025Article
- Relationship of dietary nutrients with early childhood caries and caries activity among children aged 3-5 years-a cross-sectional study.BMC pediatrics · 2024Article
- Advances in Biodegradable Polymers and Biomaterials for Medical Applications-A Review.Molecules (Basel, Switzerland) · 2023Review
- Prospects on Tuning Bioactive and Antimicrobial Denture Base Resin Materials: A Narrative Review.Polymers · 2022Review
- The Potential Antiviral Effects of Selenium Nanoparticles and Coated Surfaces.Antibiotics (Basel, Switzerland) · 2022Article
- Remineralizing Effects of Resin-Based Dental Sealants: A Systematic Review of In Vitro Studies.Polymers · 2022Review
- Development of antibacterial composite resin containing chitosan/fluoride microparticles as pit and fissure sealant to prevent caries.Journal of oral microbiology · 2022Article
- Flexural Strength, Elastic Modulus and Remineralizing Abilities of Bioactive Resin-Based Dental Sealants.Polymers · 2021Article
- Minimally Invasive Therapies for the Management of Dental Caries-A Literature Review.Dentistry journal · 2021Review
- Ecological determinants of effect of a free pit and fissure sealant program in Shanxi, China, 2017-2018.BMC oral health · 2021Article
- Dental Sealant Composition-Retention Assessment in Young Permanent Molars.Materials (Basel, Switzerland) · 2021Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
This review aimed to assess the antimicrobial effects of different antibacterial agents/compounds incorporated in resin-based dental sealants. Four databases (PubMed, MEDLINE, Web of Science and Scopus) were searched. From the 8052 records retrieved, 275 records were considered eligible for full-text screening. Nineteen studies met the inclusion criteria. Data extraction and quality assessment was performed by two independent reviewers. Six of the nineteen included studies were judged to have low risk of bias, and the rest had medium risk of bias. Compounds and particles such as zinc, tin, Selenium, chitosan, chlorhexidine, fluoride and methyl methacrylate were found to be effective in reducing the colony-forming unit counts, producing inhibition zones, reducing the optical density, reducing the metabolic activities, reducing the lactic acid and polysaccharide production and neutralizing the pH when they are added to the resin-based dental sealants. In addition, some studies showed that the antibacterial effect was not significantly different after 2 weeks, 2 months and 6 months aging in distilled water or phosphate-buffered saline. In conclusion, studies have confirmed the effectiveness of adding antibacterial agents/compounds to dental sealants. However, we should consider that these results are based on laboratory studies with a high degree of heterogeneity.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.