Evidence map›Paper›PMID 33467660›Full record

ArticleInternational journal of molecular sciences2021

Common Transcriptional Program of Liver Fibrosis in Mouse Genetic Models and Humans.

Kaja Blagotinšek Cokan, Žiga Urlep, Miha Moškon, Miha Mraz, Xiang Yi Kong, Winnie Eskild, Damjana Rozman, Peter Juvan, Tadeja Režen

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.4field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 13 citations in OpenAlex.

  1. Cross-Species Upregulation ofCurrent issues in molecular biology · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 2 countries.

Kaja Blagotinšek CokanCentre for Functional Genomics and Bio-Chips, Institute of Biochemistry and Molecular Genetics, Faculty of Medicine, University of Ljubljana, 1000 Ljubljana, Slovenia.ORCID 0000-0002-7779-8036
Žiga UrlepCentre for Functional Genomics and Bio-Chips, Institute of Biochemistry and Molecular Genetics, Faculty of Medicine, University of Ljubljana, 1000 Ljubljana, Slovenia.
Miha MoškonComputational Biology Group, Faculty of Computer and Information Science, University of Ljubljana, 1000 Ljubljana, Slovenia.ORCID 0000-0003-4600-1730
Miha MrazComputational Biology Group, Faculty of Computer and Information Science, University of Ljubljana, 1000 Ljubljana, Slovenia.
Xiang Yi KongResearch Institute of Internal Medicine, Oslo University Hospital Rikshospitalet, 0372 Oslo, Norway.
Winnie EskildSection for Biochemistry and Molecular Biology, Department of Biosciences, Faculty of Mathematics and Natural Science, University of Oslo, 0315 Oslo, Norway.ORCID 0000-0002-2690-3465
Damjana RozmanCentre for Functional Genomics and Bio-Chips, Institute of Biochemistry and Molecular Genetics, Faculty of Medicine, University of Ljubljana, 1000 Ljubljana, Slovenia.
Peter JuvanCentre for Functional Genomics and Bio-Chips, Institute of Biochemistry and Molecular Genetics, Faculty of Medicine, University of Ljubljana, 1000 Ljubljana, Slovenia.ORCID 0000-0003-2873-5247
Tadeja ReženCentre for Functional Genomics and Bio-Chips, Institute of Biochemistry and Molecular Genetics, Faculty of Medicine, University of Ljubljana, 1000 Ljubljana, Slovenia.ORCID 0000-0001-6210-7370
University of Ljubljana · SIOslo University Hospital · NOUniversity of Oslo · NO

Funding

Javna agencija za raziskovalno dejavnost RS P1-0104, P1-0390, P2-0359, J1-9176, graduate fellowship of Kaja Blagotinšek and Žiga UrlepNorges Forskningsråd NFR 240844 NCD
6 · The paper itself

Abstract

Multifactorial metabolic diseases, such as non-alcoholic fatty liver disease, are a major burden to modern societies, and frequently present with no clearly defined molecular biomarkers. Herein we used system medicine approaches to decipher signatures of liver fibrosis in mouse models with malfunction in genes from unrelated biological pathways: cholesterol synthesis-

Indexed as

AnimalsBile Acids and SaltsBiomarkersDisease Models, AnimalFatty AcidsFemaleFibrosisGenomeHumansImmune SystemInflammationLipid MetabolismLipidsLiverLiver CirrhosisMaleBile Acids and SaltsBiomarkersFatty AcidsLipidsbile acidfatty acidfibrosisGEMNAFLDNASH

Identifiers

PMID33467660
PMCPMC7830925
OpenAlexW3119300966

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.