Evidence map›Paper›PMID 33467640›Full record

ArticleInternational journal of molecular sciences2021

Modulation of p75

Sally L Elshaer, Hang-Soo Park, Laura Pearson, William D Hill, Frank M Longo, Azza B El-Remessy

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of molecular sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.8field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 9 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
  4. Article
  5. Stem Cell's Secretome Delivery Systems.Advanced pharmaceutical bulletin · 2023
    Review
  6. Article
  7. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 5 institutions in 2 countries.

Sally L ElshaerAugusta Biomedical Research Corporation, Charlie Norwood VA Medical Center, Augusta, GA 30901, USA.ORCID 0000-0002-6462-8169
Hang-Soo ParkDepartment of Surgery, University of Illinois at Chicago, Chicago, IL 60612, USA.ORCID 0000-0002-9130-8478
Laura PearsonAugusta Biomedical Research Corporation, Charlie Norwood VA Medical Center, Augusta, GA 30901, USA.
William D HillAugusta Biomedical Research Corporation, Charlie Norwood VA Medical Center, Augusta, GA 30901, USA.
Frank M LongoDepartment of Neurology and Neurological Sciences, Stanford University, Palo Alto, CA 94304, USA.
Azza B El-RemessyAugusta Biomedical Research Corporation, Charlie Norwood VA Medical Center, Augusta, GA 30901, USA.ORCID 0000-0003-4386-1989
Charlie Norwood VA Medical Center · USMansoura University · EGMedical University of South Carolina · USStanford University · USUniversity of Illinois Chicago · US

Funding

Kynurenine Pathway Regulation of CNS Senescence in Alzheimer's Disease PathologyR01AG067510 · NIA · MEDICAL UNIVERSITY OF SOUTH CAROLINA · PI HILL, WILLIAM D, MCGEE-LAWRENCE, MEGHAN E. · 2020 to 2023
$2.4M
Molecular Mechanisms of diabetic retinopathyR01EY022408 · NEI · UNIVERSITY OF GEORGIA · PI EL-REMESSY, AZZA B · 2012 to 2016
$1.5M
CSRD VA I01 CX000930NEI NIH HHS EY-022408NIA NIH HHS R01 AG067510
6 · The paper itself

Abstract

Mesenchymal stem cells (MSCs) are a promising therapy to improve vascular repair, yet their role in ischemic retinopathy is not fully understood. The aim of this study is to investigate the impact of modulating the neurotrophin receptor; p75

Indexed as

AnimalsCapillariesCell MovementCell ProliferationCoculture TechniquesCulture Media, ConditionedDisease Models, AnimalEndothelial CellsEndotheliumGene DeletionGene SilencingGreen Fluorescent ProteinsHumansIntravitreal InjectionsMesenchymal Stem CellsMiceCulture Media, ConditionedGreen Fluorescent ProteinsNerve Growth FactorNerve Tissue ProteinsNGFR protein, humanNgfr protein, mouseReceptor, Nerve Growth FactorReceptors, Nerve Growth FactorVascular Endothelial Growth Factor Aangiogenesisischemia/reperfusionischemic retinopathymesenchymal stem cellsNGFp75NTRSDF-1survivalVEGFvisual assessment

Identifiers

PMID33467640
PMCPMC7830385
OpenAlexW3120714894

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.