Evidence map›Paper›PMID 33467580›Full record

ReviewJournal of clinical medicine2021

Sex-Related Differences of Acute and Chronic Pancreatitis in Adults.

Madeline Drake, Shah-Jahan M Dodwad, Joy Davis, Lillian S Kao, Yanna Cao, Tien C Ko

Open access · goldAbstract readReview
In one paragraph

Review in Journal of clinical medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
33citing papers in PubMed, 1 pooled it
9.4field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

33 citing papers in PubMed, 1 synthesis or guideline pooled it, 68 citations in OpenAlex.

  1. Pooled it
  2. Assessing the burden and trends of pancreatitis in India from 1990-2021: An analysis of the global burden of disease database.Indian journal of gastroenterology : official journal of the Indian Society of Gastroenterology · 2026
    Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Observational
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Review
  16. Turkish Society of Gastroenterology: Pancreas Working Group, Acute Pancreatitis Committee Consensus Report.The Turkish journal of gastroenterology : the official journal of Turkish Society of Gastroenterology · 2024
    Review
  17. Genetic Variability in theInternational journal of molecular sciences · 2024
    Article
  18. Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Madeline DrakeDepartment of Surgery, UT Health Houston, Houston, TX 77030, USA.ORCID 0000-0003-3183-5505
Shah-Jahan M DodwadDepartment of Surgery, UT Health Houston, Houston, TX 77030, USA.
Joy DavisDepartment of Surgery, UT Health Houston, Houston, TX 77030, USA.
Lillian S KaoDepartment of Surgery, UT Health Houston, Houston, TX 77030, USA.
Yanna CaoDepartment of Surgery, UT Health Houston, Houston, TX 77030, USA.
Tien C KoDepartment of Surgery, UT Health Houston, Houston, TX 77030, USA.
The University of Texas Health Science Center at Houston · US

Funding

Protective Signaling Pathway in Alcohol-Induced PancreatitisR21AA027014 · NIAAA · UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON · PI KO, TIEN C · 2019 to 2020
$406k
NIAAA NIH HHS R21 AA027014
6 · The paper itself

Abstract

The incidence of acute and chronic pancreatitis is increasing in the United States. Rates of acute pancreatitis (AP) are similar in both sexes, but chronic pancreatitis (CP) is more common in males. When stratified by etiology, women have higher rates of gallstone AP, while men have higher rates of alcohol- and tobacco-related AP and CP, hypercalcemic AP, hypertriglyceridemic AP, malignancy-related AP, and type 1 autoimmune pancreatitis (AIP). No significant sex-related differences have been reported in medication-induced AP or type 2 AIP. Whether post-endoscopic retrograde cholangiopancreatography pancreatitis is sex-associated remains controversial. Animal models have demonstrated sex-related differences in the rates of induction and severity of AP, CP, and AIP. Animal and human studies have suggested that a combination of risk factor profiles, as well as genes, may be responsible for the observed differences. More investigation into the sex-related differences of AP and CP is desired in order to improve clinical management by developing effective prevention strategies, diagnostics, and therapeutics.

Indexed as

acute pancreatitisanimal modelschronic pancreatitisepidemiologysex-associated differences

Identifiers

PMID33467580
PMCPMC7830423
OpenAlexW3119810912

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.