Evidence map›Paper›PMID 33467528›Full record

ArticleToxics2021

Phylogenetic Integration Reveals the Zebrafish Core Microbiome and Its Sensitivity to Environmental Exposures.

Thomas J Sharpton, Keaton Stagaman, Michael J Sieler, Holly K Arnold, Edward W Davis

Open access · goldAbstract read
In one paragraph

Article in Toxics, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed, 1 pooled it
3.1field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 1 synthesis or guideline pooled it, 45 citations in OpenAlex.

  1. Pooled it
  2. Environmental science & technology · 2026
    Article
  3. Article
  4. Article
  5. Article
  6. DRIVERS OF VARIATION OF THE ZEBRAFISH EGG MICROBIOME.bioRxiv : the preprint server for biology · 2025
    Article
  7. Article
  8. Article
  9. Review
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Thomas J SharptonDepartment of Microbiology, Oregon State University, Corvallis, OR 97331, USA.
Keaton StagamanDepartment of Microbiology, Oregon State University, Corvallis, OR 97331, USA.ORCID 0000-0003-2815-4530
Michael J SielerDepartment of Microbiology, Oregon State University, Corvallis, OR 97331, USA.ORCID 0000-0002-8332-3408
Holly K ArnoldDepartment of Microbiology, Oregon State University, Corvallis, OR 97331, USA.
Edward W DavisCenter for Genome Research and Biocomputing, Oregon State University, Corvallis, OR 97331, USA.ORCID 0000-0003-1229-4272
Oregon State University · US

Funding

Impacts of Benzo[a]pyrene on Microbiome Development across Lifespan and Generations and the Behavioral ConsequencesR01ES030226 · NIEHS · OREGON STATE UNIVERSITY · PI SHARPTON, THOMAS JEFFERSON · 2019 to 2023
$2.1M
NIEHS NIH HHS 1R01ES030226NIEHS NIH HHS R01 ES030226
6 · The paper itself

Abstract

Zebrafish are increasingly used to study how environmental exposures impact vertebrate gut microbes. However, we understand little about which microbial taxa are common to the zebrafish gut across studies and facilities. Here, we define the zebrafish core gut microbiome to resolve microbiota that are both relatively robust to study or facility effects and likely to drive proper microbiome assembly and functioning due to their conservation. To do so, we integrated publicly available gut microbiome 16S gene sequence data from eight studies into a phylogeny and identified monophyletic clades of gut bacteria that are unexpectedly prevalent across individuals. Doing so revealed 585 core clades of bacteria in the zebrafish gut, including clades within

Indexed as

environmental exposuregut microbiomemeta-analysisphylogeneticszebrafish

Identifiers

PMID33467528
PMCPMC7829988
OpenAlexW3119355606

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.