Evidence map›Paper›PMID 33467462›Full record

ArticleMarine drugs2021

Preliminary Evaluation of 3D Printed Chitosan/Pectin Constructs for Biomedical Applications.

Georgia Michailidou, Zoe Terzopoulou, Argyroula Kehagia, Anna Michopoulou, Dimitrios N Bikiaris

Open access · goldAbstract readEvaluation Study
In one paragraph

Article in Marine drugs, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
3.3field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 50 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Georgia MichailidouLaboratory of Polymer Chemistry and Technology, Department of Chemistry, Aristotle University of Thessaloniki, 555 35 Thessaloniki, Greece.ORCID 0000-0002-9417-3767
Zoe TerzopoulouLaboratory of Polymer Chemistry and Technology, Department of Chemistry, Aristotle University of Thessaloniki, 555 35 Thessaloniki, Greece.ORCID 0000-0001-7935-2145
Argyroula KehagiaLaboratory of Polymer Chemistry and Technology, Department of Chemistry, Aristotle University of Thessaloniki, 555 35 Thessaloniki, Greece.
Anna MichopoulouBiohellenika Biotechnology Company, Leoforos Georgikis Scholis 65, 555 35 Thessaloniki, Greece.ORCID 0000-0002-4367-9370
Dimitrios N BikiarisLaboratory of Polymer Chemistry and Technology, Department of Chemistry, Aristotle University of Thessaloniki, 555 35 Thessaloniki, Greece.ORCID 0000-0001-8458-4952
Aristotle University of Thessaloniki · GRUniversity of Ioannina · GR

Funding

European Union and Greek national funds through the Operational Program Competitiveness, Entrepreneurship, and Innovation, under the call RESEARCH-CREATE-INNOVATE (project Τ1ΕΔΚ-03798). Τ1ΕΔΚ-03798
6 · The paper itself

Abstract

In the present study, chitosan (CS) and pectin (PEC) were utilized for the preparation of 3D printable inks through pneumatic extrusion for biomedical applications. CS is a polysaccharide with beneficial properties; however, its printing behavior is not satisfying, rendering the addition of a thickening agent necessary, i.e., PEC. The influence of PEC in the prepared inks was assessed through rheological measurements, altering the viscosity of the inks to be suitable for 3D printing. 3D printing conditions were optimized and the effect of different drying procedures, along with the presence or absence of a gelating agent on the CS-PEC printed scaffolds were assessed. The mean pore size along with the average filament diameter were measured through SEM micrographs. Interactions among the characteristic groups of the two polymers were evident through FTIR spectra. Swelling and hydrolysis measurements confirmed the influence of gelation and drying procedure on the subsequent behavior of the scaffolds. Ascribed to the beneficial pore size and swelling behavior, fibroblasts were able to survive upon exposure to the ungelated scaffolds.

Indexed as

Biocompatible MaterialsBiomedical EngineeringCells, CulturedCell SurvivalChitosanHumansPectinsPrinting, Three-DimensionalRheologyTissue ScaffoldsViscosityBiocompatible MaterialsChitosanPectins3D printingchitosanhydrogelspectin

Identifiers

PMID33467462
PMCPMC7829944
OpenAlexW3118280528

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.