Evidence map›Paper›PMID 33467440›Full record

ArticleCells2021

Unravelling Heterogeneity of Amplified Human Amniotic Fluid Stem Cells Sub-Populations.

Francesca Casciaro, Silvia Zia, Mattia Forcato, Manuela Zavatti, Francesca Beretti, Emma Bertucci, Andrea Zattoni, Pierluigi Reschiglian, Francesco Alviano, Laura Bonsi and 4 more

Abstract read
In one paragraph

Article in Cells, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

  1. Article
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  4. Review
  5. Review
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  7. State of the Art and New Trends from the 2022 Gism Annual Meeting.International journal of molecular sciences · 2023
    Article
  8. Article
  9. Article
  10. Review
  11. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Francesca CasciaroDepartment of Biomedical, Metabolic and Neural Sciences, University of Modena and Reggio Emilia, 41124 Modena, Italy.ORCID 0000-0002-1404-6099
Silvia ZiaStem Sel srl., 40127 Bologna, Italy.
Mattia ForcatoDepartment of Life Sciences, University of Modena and Reggio Emilia, 41124 Modena, Italy.
Manuela ZavattiDepartment of Biomedical, Metabolic and Neural Sciences, University of Modena and Reggio Emilia, 41124 Modena, Italy.ORCID 0000-0002-3454-1441
Francesca BerettiDepartment of Biomedical, Metabolic and Neural Sciences, University of Modena and Reggio Emilia, 41124 Modena, Italy.
Emma BertucciDepartment of Medical and Surgical Sciences for Mothers, Children and Adults, University of Modena and Reggio Emilia, Azienda Ospedaliero Universitaria Policlinico, 41124 Modena, Italy.
Andrea ZattoniDepartment of Chemistry "G. Ciamician", University of Bologna, 40125 Bologna, Italy.
Pierluigi ReschiglianDepartment of Chemistry "G. Ciamician", University of Bologna, 40125 Bologna, Italy.
Francesco AlvianoUnit of Histology, Embryology and Applied Biology, Department of Experimental, Diagnostic and Specialty Medicine, University of Bologna, 40125 Bologna, Italy.ORCID 0000-0002-5315-0104
Laura BonsiUnit of Histology, Embryology and Applied Biology, Department of Experimental, Diagnostic and Specialty Medicine, University of Bologna, 40125 Bologna, Italy.
Matilde Yung FolloCellular Signalling Laboratory, Department of Biomedical and Neuromotor Sciences, University of Bologna, 40125 Bologna, Italy.
Marco DemariaEuropean Research Institute for the Biology of Ageing (ERIBA), University Medical Center Groningen (UMCG), University of Groningen, 9713 Groningen, The Netherlands.ORCID 0000-0002-8429-4813
Barbara RodaDepartment of Chemistry "G. Ciamician", University of Bologna, 40125 Bologna, Italy.ORCID 0000-0003-1060-2921
Tullia MaraldiDepartment of Biomedical, Metabolic and Neural Sciences, University of Modena and Reggio Emilia, 41124 Modena, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Human amniotic fluid stem cells (hAFSCs) are broadly multipotent immature progenitor cells with high self-renewal and no tumorigenic properties. These cells, even amplified, present very variable morphology, density, intracellular composition and stemness potential, and this heterogeneity can hinder their characterization and potential use in regenerative medicine. Celector

Indexed as

Amniotic FluidCell DifferentiationCell ProliferationCells, CulturedDNA RepairGene Expression ProfilingHumansLeukocytes, MononuclearMultipotent Stem CellsRegenerative MedicineRNA-SeqSignal TransductionStem CellsTranscriptomeamniotic fluid stem cellssortingstemnesstranscriptome

Identifiers

PMID33467440
PMCPMC7830644

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.