ArticleJournal of functional morphology and kinesiology2019
The Synovium Theory: Can Exercise Prevent Knee Osteoarthritis? The Role of "Mechanokines", A Possible Biological Key.
Article in Journal of functional morphology and kinesiology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
27 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- A systematic review and meta-analysis of the efficacy of exercise therapy for the rehabilitation of rotator cuff-related shoulder pain: a subgroup analysis of racquet sport athletes.Frontiers in bioengineering and biotechnology · 2026Pooled it
- Nutraceutical supplements in management of pain and disability in osteoarthritis: a systematic review and meta-analysis of randomized clinical trials.Scientific reports · 2020Pooled it
- Frailty moderates the relation between moderate-to-vigorous physical activity & stationary time with knee osteoarthritis symptoms.The Journal of frailty & aging · 2025Observational
- Effectiveness of betamethasone dipropionate versus methylprednisolone acetate intra-articular injection in the management of pain in primary osteoarthritis of the knee.Ghana medical journal · 2025Article
- The impact of exercise on sleep and sleep disorders.Npj biological timing and sleep · 2025Review
- Strength training intervention for adult individuals with knee osteoarthritis: Establishing fidelity.Frontiers in physiology · 2025Article
- Maximizing hand function following zone II flexor tendon repair: A systematic review and meta-analysis of rehabilitation strategies.Journal of hand and microsurgery · 2024Review
- Effect of umbilical cord blood-mononuclear cells on knee osteoarthritis in rabbits.Journal of orthopaedic surgery and research · 2024Article
- Clinical Outcomes of Exercise Rehabilitation for Degenerative Tibial Meniscal Tears: A Systematic Review and Meta-Analysis of Randomized Controlled Trials.Journal of pain research · 2024Review
- Exercise Therapy for Chronic Neck Pain: Tailoring Person-Centred Approaches within Contemporary Management.Journal of clinical medicine · 2023Review
- Genistein Suppresses IL-6 and MMP-13 to Attenuate Osteoarthritis in Obese Diabetic Mice.Metabolites · 2023Article
- Why osteoarthritis of the knee is called "a wound that does not heal" and why Tai Chi is an effective treatment.Frontiers in medicine · 2023Review
- How Physical Activity Affects Knee Cartilage and a Standard Intervention Procedure for an Exercise Program: A Systematic Review.Healthcare (Basel, Switzerland) · 2022Review
- Tetrahedral framework nucleic acids promote the biological functions and related mechanism of synovium-derived mesenchymal stem cells and show improved articular cartilage regeneration activity in situ.Bioactive materials · 2022Article
- The Research Progress of Exosomes in Osteoarthritis, With Particular Emphasis on the Therapeutic Effect.Frontiers in pharmacology · 2022Review
- Increased expression of cyclooxygenase-2 in synovium tissues and synovial fluid from patients with knee osteoarthritis is associated with downregulated microRNA-758-3p expression.Experimental and therapeutic medicine · 2021Article
- Article
- Combination of magnesium ions and vitamin C alleviates synovitis and osteophyte formation in osteoarthritis of mice.Bioactive materials · 2021Article
- Overview of MMP-13 as a Promising Target for the Treatment of Osteoarthritis.International journal of molecular sciences · 2021Review
- Adapted Physical Activity to Ensure the Physical and Psychological Well-Being of COVID-19 Patients.Journal of functional morphology and kinesiology · 2021Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Osteoarthritis (OA) is a debilitating disease widespread in the world, having a negative impact on daily activities, especially in old age [...].
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.