ArticleJournal of functional morphology and kinesiology2020
Human Dental Pulp Tissue during Orthodontic Tooth Movement: An Immunofluorescence Study.
Article in Journal of functional morphology and kinesiology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
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Who cites it
10 citing papers in PubMed.
- Salivary proteomics in patients with fixed orthodontic appliances and Invisalign treatment.International dental journal · 2026Article
- Histological and Immunohistochemical Insights into Disc Perforation in the Temporomandibular Joint: A Case Report.Journal of functional morphology and kinesiology · 2025Article
- Five Numerical Methods to Assess the Ischemic Risks in Dental Pulp and Neuro-Vascular Bundle Under Orthodontic Movements in Intact Periodontium In Vitro.Dentistry journal · 2024Article
- Periodontal Breakdown, Orthodontic Movements and Pulpal Ischemia Correlations-A Comparison Between Five Study Methods.Journal of clinical medicine · 2024Article
- Ischemic Risks Induced by Larger Orthodontic Forces on Dental Pulp and Neuro-Vascular Bundle in Reduced Periodontium.Journal of clinical medicine · 2024Article
- The Effect of Larger Orthodontic Forces and Movement Types over a Dental Pulp and Neuro-Vascular Bundle of Lower Premolars in Intact Periodontium-A Numerical Analysis.Dentistry journal · 2024Article
- Assessment of the Maximum Amount of Orthodontic Force for Dental Pulp and Apical Neuro-Vascular Bundle in Intact and Reduced Periodontium on Bicuspids (Part II).International journal of environmental research and public health · 2023Article
- Assessment of the Best FEA Failure Criteria (Part II): Investigation of the Biomechanical Behavior of Dental Pulp and Apical-Neuro-Vascular Bundle in Intact and Reduced Periodontium.International journal of environmental research and public health · 2022Article
- Articular Disc of a Human Temporomandibular Joint: Evaluation through Light Microscopy, Immunofluorescence and Scanning Electron Microscopy.Journal of functional morphology and kinesiology · 2021Article
- Effects ofMaterials (Basel, Switzerland) · 2020Article
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Authors and funding
8 authors.
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Abstract
The orthodontic tooth movement is the last step of several biological processes that take place after the application of external forces. During this process, dental pulp tissue is subjected to structural and protein expression modifications in order to maintain their integrity and functional morphology. The purpose of the present work was to perform an in vivo study, evaluating protein expression modifications in the human dental pulp of patients that have undergone orthodontic tooth movement due to pre-calibrated light force application for 30 days. Dental pulp samples were extracted from molars and premolars of the control group and after 7 and 30 days of treatment; the samples were then processed for immunofluorescence reactions using antibodies against fibronectin, collagen I and vascular endothelial growth factor (VEGF). Our results show that, after 7 days of treatment, all tested proteins change their pattern expression and will reset after 30 days. These data demonstrate that the dental pulp does not involve any irreversible iatrogenic alterations, supporting the efficacy and safety of using pre-calibrated force application to induce orthodontic tooth movement in clinical practice.
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