Evidence map›Paper›PMID 33467114›Full record

ArticleDiagnostics (Basel, Switzerland)2021

Prediction of Nonalcoholic Fatty Liver Disease Using Noninvasive and Non-Imaging Procedures in Japanese Health Checkup Examinees.

Kenichiro Murayama, Michiaki Okada, Kenichi Tanaka, Chika Inadomi, Wataru Yoshioka, Yoshihito Kubotsu, Tomomi Yada, Hiroshi Isoda, Takuya Kuwashiro, Satoshi Oeda and 9 more

Open access · goldAbstract read
In one paragraph

Article in Diagnostics (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
29citing papers in PubMed, 1 pooled it
5.4field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

29 citing papers in PubMed, 1 synthesis or guideline pooled it, 47 citations in OpenAlex.

  1. Fatty liver index (FLI): more than a marker of hepatic steatosis.Journal of physiology and biochemistry · 2024
    Pooled it
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

19 authors at 5 institutions in 1 country.

Kenichiro MurayamaDivision of Metabolism and Endocrinology, Faculty of Medicine, Saga University, Saga 849-8501, Japan.
Michiaki OkadaDivision of Metabolism and Endocrinology, Faculty of Medicine, Saga University, Saga 849-8501, Japan.
Kenichi TanakaDivision of Metabolism and Endocrinology, Faculty of Medicine, Saga University, Saga 849-8501, Japan.
Chika InadomiDivision of Metabolism and Endocrinology, Faculty of Medicine, Saga University, Saga 849-8501, Japan.
Wataru YoshiokaDivision of Metabolism and Endocrinology, Faculty of Medicine, Saga University, Saga 849-8501, Japan.
Yoshihito KubotsuDivision of Metabolism and Endocrinology, Faculty of Medicine, Saga University, Saga 849-8501, Japan.
Tomomi YadaLiver Center, Saga University Hospital, Faculty of Medicine, Saga University, Saga 849-8501, Japan.
Hiroshi IsodaLiver Center, Saga University Hospital, Faculty of Medicine, Saga University, Saga 849-8501, Japan.ORCID 0000-0002-8549-6492
Takuya KuwashiroDivision of Metabolism and Endocrinology, Faculty of Medicine, Saga University, Saga 849-8501, Japan.
Satoshi OedaLiver Center, Saga University Hospital, Faculty of Medicine, Saga University, Saga 849-8501, Japan.
Takumi AkiyamaDivision of Metabolism and Endocrinology, Faculty of Medicine, Saga University, Saga 849-8501, Japan.
Noriko OzaDepartment of Hepatobiliary and Pancreatology, Saga Medical Center Koseikan, Saga 840-8571, Japan.
Hideyuki HyogoDepartment of Gastroenterology and Hepatology, JA Hiroshima General Hospital, Hatsukaichi 738-8503, Japan.
Masafumi OnoTokyo Women's Medical University Medical Center East, Internal Medicine, Tokyo 116-8567, Japan.
Takumi KawaguchiDivision of Gastroenterology, Department of Medicine, Kurume University School of Medicine, Kurume 830-0011, Japan.ORCID 0000-0002-7064-4325
Takuji TorimuraDivision of Gastroenterology, Department of Medicine, Kurume University School of Medicine, Kurume 830-0011, Japan.
Keizo AnzaiDivision of Metabolism and Endocrinology, Faculty of Medicine, Saga University, Saga 849-8501, Japan.
Yuichiro EguchiLiver Center, Saga University Hospital, Faculty of Medicine, Saga University, Saga 849-8501, Japan.
Hirokazu TakahashiDivision of Metabolism and Endocrinology, Faculty of Medicine, Saga University, Saga 849-8501, Japan.
Saga University · JPKurume University · JPHiroshima General Hospital · JPSaga-Ken Medical Centre Koseikan · JPTokyo Women's Medical University Adachi Medical Center · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Access to imaging is limited for diagnosing nonalcoholic fatty liver disease (NAFLD) in general populations. This study evaluated the diagnostic performance of noninvasive and nonimaging indexes to predict NAFLD in the general Japanese population. Health checkup examinees without hepatitis virus infection or habitual alcohol drinking were included. Fatty liver was diagnosed by ultrasonography. The hepatic steatosis index (HSI), Zhejiang University (ZJU) index, and fatty liver index (FLI) were determined, and risk of advanced liver fibrosis was evaluated by the fibrosis-4 index. NAFLD was diagnosed in 1935 (28.0%) of the 6927 subjects. The area under the receiver operating characteristic (AUROC) curve of the HSI, ZJU index, and FLI was 0.874, 0.886, and 0.884, respectively. The AUROC of the ZJU index (

Indexed as

fatty liver indexfibrosis-4 indexhealth checkuphepatic steatosis indexnonalcoholic fatty liver diseaseROCultrasonography

Identifiers

PMID33467114
PMCPMC7830542
OpenAlexW3123910101

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.