ArticleCancers2021
Thymic Hyperplasia with Lymphoepithelial Sialadenitis (LESA)-Like Features: Strong Association with Lymphomas and Non-Myasthenic Autoimmune Diseases.
Article in Cancers, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
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Who cites it
8 citing papers in PubMed, 17 citations in OpenAlex.
- Development and validation of a contrast-enhanced CT-based radiomics nomogram for differentiating mass-like thymic hyperplasia and low-risk thymoma.Journal of cancer research and clinical oncology · 2023Trial
- Rebound Thymic Hyperplasia after Recovery from Ectopic Cushing Syndrome: A Case Report and Literature Review.Endocrine, metabolic & immune disorders drug targets · 2026Review
- Thymic Hyperplasias in Practice: Clinical Context, Histological Clues, and Management Implications.Cancers · 2025Review
- Cystic Fluorodeoxyglucose-Avid Thymic Hyperplasia with Lymphoepithelial Sialadenitis-like Features.Interdisciplinary cardiovascular and thoracic surgery · 2025Article
- Multilocular Thymic Cyst with High FJournal of clinical medicine · 2025Article
- Micronodular thymic epithelial tumors with lymphoid hyperplasia and mimicking lesions.Histology and histopathology · 2025Review
- Diagnostic approach to prevascular (anterior) mediastinal lymphomas: when thoracic pathology meets hematopathology.Mediastinum (Hong Kong, China) · 2023Review
- GTF2I Mutation in Thymomas: Independence From Racial-Ethnic Backgrounds. An Indian/German Comparative Study.Pathology oncology research : POR · 2021Article
Corrections and comments
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Authors and funding
22 authors at 10 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Thymic hyperplasia (TH) with lymphoepithelial sialadenitis (LESA)-like features (LESA-like TH) has been described as a tumor-like, benign proliferation of thymic epithelial cells and lymphoid follicles. We aimed to determine the frequency of lymphoma and autoimmunity in LESA-like TH and performed retrospective analysis of cases with LESA-like TH and/or thymic MALT-lymphoma. Among 36 patients (21 males) with LESA-like TH (age 52 years, 32-80; lesion diameter 7.0 cm, 1-14.5; median, range), five (14%) showed associated lymphomas, including four (11%) thymic MALT lymphomas and one (3%) diffuse large B-cell lymphoma. One additional case showed a clonal B-cell-receptor rearrangement without evidence of lymphoma. Twelve (33%) patients (7 women) suffered from partially overlapping autoimmune diseases: systemic lupus erythematosus (
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.