Evidence map›Paper›PMID 33466998›Full record

ArticleMolecules (Basel, Switzerland)2021

Development of Antimicrobial Stapled Peptides Based on Magainin 2 Sequence.

Motoharu Hirano, Chihiro Saito, Hidetomo Yokoo, Chihiro Goto, Ryuji Kawano, Takashi Misawa, Yosuke Demizu

Abstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

28 citing papers in PubMed.

  1. Review
  2. Review
  3. Aromatic Amide Foldamers Show Conformation-Dependent Electronic Properties.Chemphyschem : a European journal of chemical physics and physical chemistry · 2025
    Article
  4. Article
  5. Article
  6. Review
  7. Review
  8. Review
  9. Review
  10. Review
  11. Review
  12. Article
  13. Article
  14. Peptide Stapling Applied to Antimicrobial Peptides.Antibiotics (Basel, Switzerland) · 2023
    Review
  15. Article
  16. Review
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Motoharu HiranoDivision of Organic Chemistry, National Institute of Health Sciences, 3-25-26, Tonomachi, Kawasaki, Kanagawa 210-9501, Japan.
Chihiro SaitoDepartment of Biotechnology and Life Science, Tokyo University of Agriculture and Technology, 2-24-6 Naka-cho, Koganei, Tokyo 184-8588, Japan.
Hidetomo YokooDivision of Organic Chemistry, National Institute of Health Sciences, 3-25-26, Tonomachi, Kawasaki, Kanagawa 210-9501, Japan.
Chihiro GotoDivision of Organic Chemistry, National Institute of Health Sciences, 3-25-26, Tonomachi, Kawasaki, Kanagawa 210-9501, Japan.
Ryuji KawanoDepartment of Biotechnology and Life Science, Tokyo University of Agriculture and Technology, 2-24-6 Naka-cho, Koganei, Tokyo 184-8588, Japan.ORCID 0000-0001-6523-0649
Takashi MisawaDivision of Organic Chemistry, National Institute of Health Sciences, 3-25-26, Tonomachi, Kawasaki, Kanagawa 210-9501, Japan.
Yosuke DemizuDivision of Organic Chemistry, National Institute of Health Sciences, 3-25-26, Tonomachi, Kawasaki, Kanagawa 210-9501, Japan.ORCID 0000-0001-7521-4861

Funding

Japan Agency for Medical Research and Development 20mk0101120j0003Japan Society for the Promotion of Science 20k22711, H.Y.; 18k14880, T.M.; 17k08385 and 18H05502, Y.D.Takeda Science foundation Y.D.TERUMO FOUNDATION for Life Sciences and ARTS Y.D.the Kobayashi Foundation for Cancer Research Y.D.the Naito Foundation Y.D.the NOVARTIS Foundation (Japan) for the Promotion of Science Y.D.the Sumitomo Foundation Y.D.
6 · The paper itself

Abstract

Magainin 2 (

Indexed as

Anti-Bacterial AgentsMagaininsXenopus ProteinsAmino Acid SequenceAnimalsGram-Negative BacteriaGram-Positive BacteriaXenopus laevisAnti-Bacterial AgentsMagaininsXenopus Proteinsamphipathicityantimicrobial peptideshelical structuremagainin 2stapled peptide

Identifiers

PMID33466998
PMCPMC7830303

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.