ArticleMaterials (Basel, Switzerland)2021
Comparative Study of Gelatin Hydrogels Modified by Various Cross-Linking Agents.
Article in Materials (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 80 papers.
What it found
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Who cites it
80 citing papers in PubMed, 208 citations in OpenAlex.
- Multifunctional hydrogel scaffolds for endogenous osteochondral regeneration.Regenerative therapy · 2026Review
- Gelatin Hydrogel Crosslinking: From Molecular Design to Functional Soft Materials.Gels (Basel, Switzerland) · 2026Review
- Development and evaluation of a gelatin-integrated wool hydrogel dressing for enhanced wound healing using in vitro and in vivo models.Biomaterials and biosystems · 2026Article
- Smart Polymeric Wound Dressings for Wound Treatment: Contributions and Applications.International journal of molecular sciences · 2026Review
- Structural and Antimicrobial Characterization of Porcine and Fish Gelatin Hydrogels Photochemically Crosslinked with Menadione Sodium Bisulfite.Gels (Basel, Switzerland) · 2026Article
- Characterization of Hydrogels of Gelatin/O-Carboxymethyl Chitosan in Ovule Form with Curcumin and Retinyl Palmitate as a Treatment for Cervical Cancer.Gels (Basel, Switzerland) · 2026Article
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- Biocompatible Photocrosslinked Chitosan- and Gelatin-Based Hydrogels for Wound Healing Applications.Gels (Basel, Switzerland) · 2026Article
- Effect of Biopolymer Additives on Functional Properties of Alginate-Based Composite Hydrogels.Gels (Basel, Switzerland) · 2026Review
- Interpenetrating gelatin/sodium alginate hydrogel with controlled PRP lysate delivery for accelerating diabetic wound healing with reduced scarring.RSC advances · 2026Article
- Gelatin-Chitosan-PVA Hydrogels IncorporatingGels (Basel, Switzerland) · 2026Article
- Exploring Compositions of Cell-Based Therapies for Diabetic Foot Ulcer Treatment: A Review of Clinical Studies.Stem cell reviews and reports · 2026Review
- i-Rheo-Indent: Broadband rheological characterisation of soft solids by macroscale indentation.Rheologica acta · 2026Article
- Enhanced Vascularity in Gelatin Scaffolds via Copper-Doped Magnesium-Calcium Silicates Incorporation:ArXiv · 2025Article
- Hydrogel-based microfluidic model of the blood-brain barrier: progress and future perspectives.Fluids and barriers of the CNS · 2025Review
- Polydopamine-based electrochemical immunosensor for sensitive and selective detection of cotinine.RSC advances · 2025Article
- Fabrication of Free-Standing Gelatin Thin Films via the Gelation and Drying of Liquid Foam Films.Langmuir : the ACS journal of surfaces and colloids · 2025Article
- In Vitro Characterization of Biodegradable Polyurethane Foams With Facile Gelatin Modification for Traumatic Wound Hemostasis and Regeneration.Journal of biomedical materials research. Part A · 2025Article
20 more citing papers are in PubMed but not listed here.
Corrections and comments
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
Abstract
Gelatin is a natural biopolymer derived from collagen. Due to its many advantages, such as swelling capacity, biodegradability, biocompatibility, and commercial availability, gelatin is widely used in the field of pharmacy, medicine, and the food industry. Gelatin solutions easily form hydrogels during cooling, however, the materials are mechanically poor. To improve their properties, they are often chemically crosslinked. The cross-linking agents are divided into two groups: Zero-length and non-zero-length cross-linkers. In this study, gelatin was cross-linked by three different cross-linking agents: EDC-NHS, as a typically used cross-linker, and also squaric acid (SQ) and dialdehyde starch (DAS), as representatives of a second group of cross-linkers. For all prepared gelatin hydrogels, mechanical strength tests, thermal analysis, infrared spectroscopy, swelling ability, and SEM images were performed. The results indicate that the dialdehyde starch is a better cross-linking agent for gelatin than EDC-NHS. Meanwhile, the use of squaric acid does not give beneficial changes to the properties of the hydrogel.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.