Evidence map›Paper›PMID 33466888›Full record

ArticleMolecules (Basel, Switzerland)2021

Revisiting the Rate-Limiting Step of the ANS-Protein Binding at the Protein Surface and Inside the Hydrophobic Cavity.

Chikashi Ota, Shun-Ichi Tanaka, Kazufumi Takano

Abstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

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  8. Highly stableFrontiers in bioengineering and biotechnology · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Chikashi OtaCollege of Life Sciences, Ritsumeikan University, Kusatsu, Shiga 525-8577, Japan.
Shun-Ichi TanakaDepartment of Biomolecular Chemistry, Kyoto Prefectural University, Sakyo-ku, Kyoto 606-8522, Japan.
Kazufumi TakanoDepartment of Biomolecular Chemistry, Kyoto Prefectural University, Sakyo-ku, Kyoto 606-8522, Japan.ORCID 0000-0002-7548-7314

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

8-Anilino-1-naphthalenesulfonic acid (ANS) is used as a hydrophobic fluorescence probe due to its high intensity in hydrophobic environments, and also as a microenvironment probe because of its unique ability to exhibit peak shift and intensity change depending on the surrounding solvent environment. The difference in fluorescence can not only be caused by the microenvironment but can also be affected by the binding affinity, which is represented by the binding constant (

Indexed as

Anilino NaphthalenesulfonatesAnimalsBinding SitesCattleEnergy TransferFluorescent DyesHydrophobic and Hydrophilic InteractionsMuramidaseProtein BindingProtein ConformationSerum Albumin, Bovine8-anilino-1-naphthalenesulfonic acidAnilino NaphthalenesulfonatesFluorescent DyesMuramidaseSerum Albumin, Bovine8-anilino-1-naphthalenesulfonic acidfluorescencehydrophobic probeprotein binding

Identifiers

PMID33466888
PMCPMC7830758

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.