Evidence map›Paper›PMID 33466804›Full record

ArticleMolecules (Basel, Switzerland)2021

Phytochemical and Biological Evaluation of a Newly Designed Nutraceutical Self-Nanoemulsifying Self-Nanosuspension for Protection and Treatment of Cisplatin Induced Testicular Toxicity in Male Rats.

Sherif R Abdel-All, Zeinab T Abdel Shakour, Dalia M N Abouhussein, Enji Reda, Thoraya F Sallam, Hala M El-Hefnawy, Azza R Abdel-Monem

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Molecules (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Sherif R Abdel-AllPhytochemistry and Natural Product Department, Egyptian Drug Authority, Giza 12553, Egypt.
Zeinab T Abdel ShakourPhytochemistry and Natural Product Department, Egyptian Drug Authority, Giza 12553, Egypt.ORCID 0000-0002-8395-3629
Dalia M N AbouhusseinPharmaceutics Department, Egyptian Drug Authority, Giza 12553, Egypt.ORCID 0000-0002-1207-6091
Enji RedaPharmacology and Toxicology Department, Faculty of Pharmacy, Sinai University, East Kantara Branch, New City, El Ismailia 41611, Egypt.
Thoraya F SallamHistology and Cytology Department, Faculty of Veterinary Medicine, Cairo University, Giza 12211, Egypt.
Hala M El-HefnawyPharmacognosy Department, Faculty of Pharmacy, Cairo University, Cairo 11562, Egypt.
Azza R Abdel-MonemPharmacognosy Department, Faculty of Pharmacy, Cairo University, Cairo 11562, Egypt.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The incorporation of cisplatin (CP) as a cytotoxic antineoplastic agent in most chemotherapeutic protocols is a challenge due to its toxic effect on testicular tissues. Natural compounds present a promising trend in research, so a new nutraceutical formulation (NCF) was designed to diminish CP spermatotoxicity. A combination of three nutraceutical materials, 250 mg

Indexed as

Administration, OralAnimalsAntineoplastic AgentsCisplatinDietary SupplementsEmulsionsMaleNanoparticlesPhytochemicalsProtective AgentsRatsRats, WistarSpirulinaTestisAntineoplastic AgentsCisplatinEmulsionsPhytochemicalsProtective Agentsbiochemical markerscisplatinfish oilhistopathologynew nutraceutical formulationSNESNSSpirulina platensisTribulus terrestris L.

Identifiers

PMID33466804
PMCPMC7830605

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.