Evidence map›Paper›PMID 33466803›Full record

ReviewLife (Basel, Switzerland)2021

Long Non-Coding RNAs and Their Potential Roles in the Vector-Host-Pathogen Triad.

Parwez Ahmad, Chaima Bensaoud, Imen Mekki, Mujeeb Ur Rehman, Michail Kotsyfakis

Open access · goldAbstract readReview
In one paragraph

Review in Life (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
29citing papers in PubMed, 1 pooled it
3.1field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

29 citing papers in PubMed, 1 synthesis or guideline pooled it, 48 citations in OpenAlex.

  1. Pooled it
  2. Long non-coding RNA maternally expressed gene 3 (Turkish journal of obstetrics and gynecology · 2026
    Article
  3. Review
  4. Article
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  6. Article
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  8. Review
  9. Review
  10. Article
  11. Review
  12. Article
  13. Article
  14. Review
  15. Article
  16. Long Noncoding RNAs in Taxane Resistance of Breast Cancer.International journal of molecular sciences · 2023
    Review
  17. Editorial: Special Issue on the "Molecular Biology of Disease Vectors".International journal of molecular sciences · 2023
    Article
  18. Review
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 2 countries.

Parwez AhmadInstitute of Parasitology, Biology Centre, Czech Academy of Sciences, 37005 Ceske Budejovice (Budweis), Czech Republic.
Chaima BensaoudInstitute of Parasitology, Biology Centre, Czech Academy of Sciences, 37005 Ceske Budejovice (Budweis), Czech Republic.
Imen MekkiInstitute of Parasitology, Biology Centre, Czech Academy of Sciences, 37005 Ceske Budejovice (Budweis), Czech Republic.
Mujeeb Ur RehmanKey Laboratory of Animal Disease and Human Health of Sichuan Province, Sichuan Agricultural University, Wenjiang, Chengdu 611130, China.ORCID 0000-0002-5078-5657
Michail KotsyfakisInstitute of Parasitology, Biology Centre, Czech Academy of Sciences, 37005 Ceske Budejovice (Budweis), Czech Republic.ORCID 0000-0002-7526-1876
Institute of Parasitology · CZSichuan Agricultural University · CNUniversity of South Bohemia in České Budějovice · CZ

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Long non-coding (lnc)RNAs have emerged as critical regulators of gene expression and are involved in almost every cellular process. They can bind to other molecules including DNA, proteins, or even other RNA types such messenger RNA or small RNAs. LncRNAs are typically expressed at much lower levels than mRNA, and their expression is often restricted to tissue- or time-specific developmental stages. They are also involved in several inter-species interactions, including vector-host-pathogen interactions, where they can be either vector/host-derived or encoded by pathogens. In these interactions, they function via multiple mechanisms including regulating pathogen growth and replication or via cell-autonomous antimicrobial defense mechanisms. Recent advances suggest that characterizing lncRNAs and their targets in different species may hold the key to understanding the role of this class of non-coding RNA in interspecies crosstalk. In this review, we present a general overview of recent studies related to lncRNA-related regulation of gene expression as well as their possible involvement in regulating vector-host-pathogen interactions.

Indexed as

lncRNAncRNAvector–host–pathogen interactions

Identifiers

PMID33466803
PMCPMC7830631
OpenAlexW3119545672

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.