Evidence map›Paper›PMID 33466789›Full record

ArticleInternational journal of molecular sciences2021

In Silico Identification of the Complex Interplay between Regulatory SNPs, Transcription Factors, and Their Related Genes in

Selina Klees, Thomas Martin Lange, Hendrik Bertram, Abirami Rajavel, Johanna-Sophie Schlüter, Kun Lu, Armin Otto Schmitt, Mehmet Gültas

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 1 pooled it
1.5field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 1 synthesis or guideline pooled it, 21 citations in OpenAlex.

  1. Pooled it
  2. Genetic dissection of oil content in maize kernel using combined genome-wide association analysis and linkage mapping.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2026
    Article
  3. Article
  4. Article
  5. Article
  6. Genome-wide chromatin accessibility analysis unveils open chromatin convergent evolution during polyploidization in cotton.Proceedings of the National Academy of Sciences of the United States of America · 2022
    Article
  7. Article
  8. Article
  9. Deciphering Pleiotropic Signatures of Regulatory SNPs inInternational journal of molecular sciences · 2022
    Article
  10. Article
  11. Article
  12. Article
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 2 countries.

Selina KleesBreeding Informatics Group, Department of Animal Sciences, Georg-August University, Margarethe von Wrangell-Weg 7, 37075 Göttingen, Germany.ORCID 0000-0001-7640-6523
Thomas Martin LangeBreeding Informatics Group, Department of Animal Sciences, Georg-August University, Margarethe von Wrangell-Weg 7, 37075 Göttingen, Germany.ORCID 0000-0003-4351-7950
Hendrik BertramBreeding Informatics Group, Department of Animal Sciences, Georg-August University, Margarethe von Wrangell-Weg 7, 37075 Göttingen, Germany.ORCID 0000-0002-6517-9940
Abirami RajavelBreeding Informatics Group, Department of Animal Sciences, Georg-August University, Margarethe von Wrangell-Weg 7, 37075 Göttingen, Germany.ORCID 0000-0003-4179-2668
Johanna-Sophie SchlüterBreeding Informatics Group, Department of Animal Sciences, Georg-August University, Margarethe von Wrangell-Weg 7, 37075 Göttingen, Germany.ORCID 0000-0002-9019-304X
Kun LuCollege of Agronomy and Biotechnology, Southwest University, Chongqing 400715, China.ORCID 0000-0003-1370-8633
Armin Otto SchmittBreeding Informatics Group, Department of Animal Sciences, Georg-August University, Margarethe von Wrangell-Weg 7, 37075 Göttingen, Germany.ORCID 0000-0002-4910-9467
Mehmet GültasBreeding Informatics Group, Department of Animal Sciences, Georg-August University, Margarethe von Wrangell-Weg 7, 37075 Göttingen, Germany.ORCID 0000-0003-3297-3192
University of Göttingen · DESouthwest University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Regulatory SNPs (rSNPs) are a special class of SNPs which have a high potential to affect the phenotype due to their impact on DNA-binding of transcription factors (TFs). Thus, the knowledge about such rSNPs and TFs could provide essential information regarding different genetic programs, such as tissue development or environmental stress responses. In this study, we use a multi-omics approach by combining genomics, transcriptomics, and proteomics data of two different

Indexed as

Computer SimulationGene Expression Regulation, PlantPolymorphism, Single NucleotideAlgorithmsBrassica napusComputational BiologyFlowersGene Expression ProfilingGenomicsPlant LeavesPlant ProteinsPlant RootsPlant StemsProteomicsSpecies SpecificityTranscription FactorsPlant ProteinsTranscription FactorsDOFgene expressionmulti-omicsrandom forestrSNPstranscription factor

Identifiers

PMID33466789
PMCPMC7830561
OpenAlexW3118795041

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.