Evidence map›Paper›PMID 33466784›Full record

ReviewCancers2021

Allogeneic Stem Cell Transplantation in Mantle Cell Lymphoma in the Era of New Drugs and CAR-T Cell Therapy.

Miriam Marangon, Carlo Visco, Anna Maria Barbui, Annalisa Chiappella, Alberto Fabbri, Simone Ferrero, Sara Galimberti, Stefano Luminari, Gerardo Musuraca, Alessandro Re and 2 more

Open access · goldAbstract readReview
In one paragraph

Review in Cancers, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 1 pooled it
1.9field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 1 synthesis or guideline pooled it, 24 citations in OpenAlex.

  1. [The guideline of the diagnosis and treatment of mantle cell lymphoma in China (2022)].Zhonghua xue ye xue za zhi = Zhonghua xueyexue zazhi · 2022
    Guideline
  2. Article
  3. Article
  4. Article
  5. Review
  6. Tackling Mantle Cell Lymphoma in Europe.Healthcare (Basel, Switzerland) · 2022
    Article
  7. Review
  8. Review
  9. Article
  10. Article
  11. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 12 institutions in 1 country.

Miriam MarangonDepartment of Hematology, Azienda Sanitaria Universitaria Giuliano Isontina, 34129 Trieste, Italy.
Carlo ViscoSection of Hematology, Department of Medicine, University of Verona, 37134 Verona, Italy.ORCID 0000-0003-2863-0883
Anna Maria BarbuiHematology Unit, ASST Papa Giovanni XXIII, 24127 Bergamo, Italy.
Annalisa ChiappellaDivision of Hematology, Fondazione IRCCS, Istituto Nazionale dei Tumori, 20133 Milan, Italy.
Alberto FabbriHematology Division, Department of Oncology, Azienda Ospedaliero-Universitaria Senese, 53100 Siena, Italy.
Simone FerreroHematology Division, Department of Molecular Biotechnologies and Health Sciences, Università di Torino, 10126 Torino, Italy.ORCID 0000-0002-9711-1502
Sara GalimbertiHematology Unit, Department of Clinical and Experimental Medicine, University of Pisa, 56126 Pisa, Italy.ORCID 0000-0001-7899-5966
Stefano LuminariHematology Unit, Azienda Unità Sanitaria Locale IRCCS di Reggio Emilia, 42123 Modena, Italy.
Gerardo MusuracaDepartment of Hematology, IRCCS-Istituto Scientifico Romagnolo per lo Studio e la Cura dei Tumori (I.R.S.T.), 47014 Meldola, Italy.
Alessandro ReHematology Unit, ASST Spedali Civili, 25123 Brescia, Italy.ORCID 0000-0003-1156-6395
Vittorio Ruggero ZilioliDivision of Hematology, ASST Grande Ospedale Metropolitano Niguarda, 20162 Milan, Italy.
Marco LadettoSC Ematologia, Azienda Ospedaliera Santi Antonio e Biagio e Cesare Arrigo, 15121 Alessandria, Italy.
Azienda Ospedaliera Citta' della Salute e della Scienza di Torino · ITAzienda Ospedaliera Universitaria Senese · ITAzienda Sanitaria Universitaria Integrata di Trieste · ITAzienda Socio Sanitaria Territoriale degli Spedali Civili di Brescia · ITAzienda Socio Sanitaria Territoriale Grande Ospedale Metropolitano Niguarda · ITFondazione IRCCS Istituto Nazionale dei Tumori · ITIstituto Scientifico Romagnolo per lo Studio e la Cura dei Tumori · ITOspedale Papa Giovanni XXIII · ITUniversità degli Studi del Piemonte Orientale “Amedeo Avogadro” · ITUniversity of Modena and Reggio Emilia · ITUniversity of Pisa · ITUniversity of Verona · IT

Funding

Cilag N/AMattioli 1885 N/A
6 · The paper itself

Abstract

MCL is an uncommon lymphoproliferative disorder that has been regarded as incurable since its identification as a distinct entity. Allogeneic transplantation for two decades has represented the only option capable of ensuring prolonged remissions and possibly cure. Despite its efficacy, its application has been limited by feasibility limitations and substantial toxicity, particularly in elderly patients. Nevertheless, the experience accumulated over time has been wide though often scattered among retrospective and small prospective studies. In this review, we aimed at critically revise and discuss available evidence on allogeneic transplantation in MCL, trying to put available evidence into the 2020 perspective, characterized by unprecedented development of novel promising therapeutic agents and regimens.

Indexed as

allogeneic stem cell transplantationCar-T cell therapymantle cell lymphoma

Identifiers

PMID33466784
PMCPMC7830938
OpenAlexW3119049156

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.