ArticleBrain sciences2021
The Effects of Spinal Manipulation on Motor Unit Behavior.
Article in Brain sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
10 citing papers in PubMed, 17 citations in OpenAlex.
- Immediate clinical and neuromechanical effects of cervical spine manipulation compared to cervical spine mobilization among individuals with chronic neck pain: a randomized mechanistic cross-over trial.Chiropractic & manual therapies · 2026Trial
- Immediate effects of upper cervical spinal manipulation on cervical sensorimotor control in individuals with chronic primary cervical pain: an exploratory randomized controlled trial.Chiropractic & manual therapies · 2026Trial
- Neurophysiological Response of Spinal Mobilization and Manipulation in Individuals With and Without Musculoskeletal Spine Disorders: A Scoping Review.The European journal of neuroscience · 2026Article
- Technologies to investigate the mechanisms of force-based manipulations: a narrative methods review.Frontiers in pain research (Lausanne, Switzerland) · 2026Review
- The Impact of a Single Hip Manipulation on Quadriceps Activity and Performance: A Randomized Study.Biomedicines · 2025Article
- Neuromuscular Response to High-Velocity, Low-Amplitude Spinal Manipulation-An Overview.Medicina (Kaunas, Lithuania) · 2025Review
- Neuroplastic Responses to Chiropractic Care: Broad Impacts on Pain, Mood, Sleep, and Quality of Life.Brain sciences · 2024Article
- Hip Manipulation Increases Electromyography Amplitude and Hip Joint Performance: A Double-Blind Randomized Controlled Study.Life (Basel, Switzerland) · 2024Article
- The Neurophysiological Lesion: A Scoping Review.Journal of chiropractic medicine · 2023Article
- The Changes of Brain Function After Spinal Manipulation Therapy in Patients with Chronic Low Back Pain: A Rest BOLD fMRI Study.Neuropsychiatric disease and treatment · 2022Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors at 4 institutions in 4 countries.
Funding
Abstract
Over recent years, a growing body of research has highlighted the neural plastic effects of spinal manipulation on the central nervous system. Recently, it has been shown that spinal manipulation improved outcomes, such as maximum voluntary force and limb joint position sense, reflecting improved sensorimotor integration and processing. This study aimed to further evaluate how spinal manipulation can alter neuromuscular activity. High density electromyography (HD sEMG) signals from the tibialis anterior were recorded and decomposed in order to study motor unit changes in 14 subjects following spinal manipulation or a passive movement control session in a crossover study design. Participants were asked to produce ankle dorsiflexion at two force levels, 5% and 10% of maximum voluntary contraction (MVC), following two different patterns of force production ("ramp" and "ramp and maintain"). A significant decrease in the conduction velocity (
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.