Evidence map›Paper›PMID 33466689›Full record

ArticleMarine drugs2021

In Vitro Chemopreventive Potential of Phlorotannins-Rich Extract from Brown Algae by Inhibition of Benzo[a]pyrene-Induced P2X7 Activation and Toxic Effects.

Mélody Dutot, Elodie Olivier, Sophie Fouyet, Romain Magny, Karim Hammad, Emmanuel Roulland, Patrice Rat, Roxane Fagon

Open access · goldAbstract read
In one paragraph

Article in Marine drugs, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.1field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 17 citations in OpenAlex.

  1. Enzymatic Hydrolysates fromMarine drugs · 2026
    Article
  2. Review
  3. Review
  4. Review
  5. Review
  6. Article
  7. Review
  8. Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Mélody DutotRecherche & Développement, Yslab, 29000 Quimper, France.ORCID 0000-0003-0964-0664
Elodie OlivierFaculté de Pharmacie de Paris, UMR CNRS 8038, Université de Paris, 75006 Paris, France.
Sophie FouyetFaculté de Pharmacie de Paris, UMR CNRS 8038, Université de Paris, 75006 Paris, France.
Romain MagnyFaculté de Pharmacie de Paris, UMR CNRS 8038, Université de Paris, 75006 Paris, France.
Karim HammadFaculté de Pharmacie de Paris, UMR CNRS 8038, Université de Paris, 75006 Paris, France.
Emmanuel RoullandFaculté de Pharmacie de Paris, UMR CNRS 8038, Université de Paris, 75006 Paris, France.ORCID 0000-0002-8012-7946
Patrice RatFaculté de Pharmacie de Paris, UMR CNRS 8038, Université de Paris, 75006 Paris, France.ORCID 0000-0003-1270-4761
Roxane FagonRecherche & Développement, Yslab, 29000 Quimper, France.
Centre National de la Recherche Scientifique · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Phlorotannins are polyphenols occurring exclusively in some species of brown algae, known for numerous biological activities, e.g., antioxidant, antiproliferative, antidiabetic, and antiallergic properties. Their effects on the response of human lung cells to benzo[a]pyrene (B[a]P) has not been characterized. Our objective was to in vitro evaluate the effects of a phlorotannin-rich extract obtained from the brown algae

Indexed as

PhaeophyceaeA549 CellsBenzo(a)pyreneChemopreventionDose-Response Relationship, DrugHumansReceptors, Purinergic P2X7TanninsBenzo(a)pyreneReceptors, Purinergic P2X7TanninsA549 cellscancercytoskeletonP2X7 receptorphlorotanninspollution

Identifiers

PMID33466689
PMCPMC7828825
OpenAlexW3120207412

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.