Evidence map›Paper›PMID 33466627›Full record

Trial reportNutrients2021

The Acute and Chronic Cognitive Effects of a Sage Extract: A Randomized, Placebo Controlled Study in Healthy Humans.

Emma L Wightman, Philippa A Jackson, Bethany Spittlehouse, Thomas Heffernan, Damien Guillemet, David O Kennedy

Open access · goldAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Nutrients, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
4.6field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 22 citations in OpenAlex.

  1. Trial
  2. Trial
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  4. Trial
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  7. Review
  8. Article
  9. An Ethnopharmacological Survey on Medicinally Important Plants of Genus Salvia.Combinatorial chemistry & high throughput screening · 2025
    Review
  10. Review
  11. Natural Compounds ofBiomedicines · 2023
    Review
  12. Article
  13. A Focused Review on Cognitive Improvement by the GenusPharmaceuticals (Basel, Switzerland) · 2023
    Review
  14. Article
  15. Article
  16. Review
  17. Acute Effects ofFrontiers in nutrition · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 2 countries.

Emma L WightmanBrain Performance and Nutrition Research Centre, Northumbria University, Newcastle Upon Tyne NE1 8ST, UK.
Philippa A JacksonBrain Performance and Nutrition Research Centre, Northumbria University, Newcastle Upon Tyne NE1 8ST, UK.ORCID 0000-0002-9492-134X
Bethany SpittlehouseBrain Performance and Nutrition Research Centre, Northumbria University, Newcastle Upon Tyne NE1 8ST, UK.
Thomas HeffernanBrain Performance and Nutrition Research Centre, Northumbria University, Newcastle Upon Tyne NE1 8ST, UK.
Damien GuillemetNexira SAS, 129 Chemin de Croisset-CS 94151, 76723 Rouen, France.ORCID 0000-0002-6638-0531
David O KennedyBrain Performance and Nutrition Research Centre, Northumbria University, Newcastle Upon Tyne NE1 8ST, UK.
Northumbria University · GBNexira (France) · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The sage (

Indexed as

Administration, OralAdultCognitionFemaleHumansMaleMemoryMiddle AgedPlant ExtractsPolyphenolsPsychological TestsSalviaSalvia officinalisPlant ExtractsPolyphenolscognitionpolyphenolssageSalvia lavandulaefoliaSalvia officinalis

Identifiers

PMID33466627
PMCPMC7828691
OpenAlexW3120764788

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.