ArticleAnimals : an open access journal from MDPI2021
Luteinizing Hormone Effect on Luteal Cells Is Dependent on the Corpus Luteum Stage in Felids.
Article in Animals : an open access journal from MDPI, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
3 citing papers in PubMed, 7 citations in OpenAlex.
- Administration of Human Chorionic Gonadotropin Combined with Phenylbutazone at the Time of Embryo Transfer Synergistically Improves Pregnancy Rates in Dromedary Camels.Veterinary sciences · 2026Article
- Development of a 3D in vitro model to study corpus luteum of felids based on luteinized cells from antral follicles.Cell and tissue research · 2025Article
- Phoenixin-14 as a novel direct regulator of porcine luteal cell functions†.Biology of reproduction · 2024Article
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
Abstract
The objective of this study was to investigate the effect of luteinizing hormone (LH) on steroidogenic luteal cells obtained from corpora lutea (CL) of the domestic cat and selected wild felids. Luteal cells were isolated enzymatically from CL at different developmental stages and cultured for two days in the presence and absence of 100 ng/mL LH, respectively. Functionality was assessed by progesterone (P4) accumulation in cell culture media determined by ELISA. In addition, steroidogenic function was confirmed using immunohistochemistry for 3β-hydroxysteroid dehydrogenase (HSD3B). The enzymatic method allowed for the isolation of mostly small luteal cells in all investigated felids. Treatment with LH resulted in an increase in P4 secretion of cultured luteal cells obtained from CL in the formation stage (African lion) and development/maintenance stage (domestic cat (
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