Evidence map›Paper›PMID 33466486›Full record

ReviewMolecules (Basel, Switzerland)2021

Cyanobacteria as Natural Therapeutics and Pharmaceutical Potential: Role in Antitumor Activity and as Nanovectors.

Hina Qamar, Kashif Hussain, Aishwarya Soni, Anish Khan, Touseef Hussain, Benoît Chénais

Open access · goldAbstract readReview
In one paragraph

Review in Molecules (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed
2.2field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 62 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 5 institutions in 2 countries.

Hina QamarInterdisciplinary Biotechnology Unit, Aligarh Muslim University, Aligarh 202002, India.ORCID 0000-0003-2834-0683
Kashif HussainPharmacy Section, Gyani Inder Singh Institute of Professional Studies, Dehradun 248003, India.
Aishwarya SoniDepartment of Biotechnology, Deenbandhu Chhotu Ram University of Science and Technology, Murthal, Sonepat 131039, India.
Anish KhanCentre for Biotechnology, Maharshi Dayanand University, Rohtak 124001, India.
Touseef HussainDepartment of Botany, Aligarh Muslim University, Aligarh 202002, India.ORCID 0000-0002-3325-0423
Benoît ChénaisEA 2160 Mer Molécules Santé, Le Mans Université, F-72085 Le Mans, France.ORCID 0000-0003-2441-1966
Aligarh Muslim University · INDeenbandhu Chhotu Ram University of Science and Technology · INGlocal University · INLe Mans Université · FRMaharshi Dayanand University · IN

Funding

Ligue Contre le Cancer, comité de la Sarthe IRAPIM
6 · The paper itself

Abstract

Cyanobacteria (blue-green microalgae) are ubiquitous, Gram-negative photoautotrophic prokaryotes. They are considered as one of the most efficient sources of bioactive secondary metabolites. More than 50% of cyanobacteria are cultivated on commercial platforms to extract bioactive compounds, which have bene shown to possess anticancer activity. The chemically diverse natural compounds or their analogues induce cytotoxicity and potentially kill a variety of cancer cells via the induction of apoptosis, or altering the activation of cell signaling, involving especially the protein kinase-C family members, cell cycle arrest, mitochondrial dysfunctions and oxidative damage. These therapeutic properties enable their use in the pharma and healthcare sectors for the betterment of future generations. This review provides a baseline overview of the anti-cancerous cyanobacterial bioactive compounds, along with recently introduced nanomaterials that could be used for the development of new anticancer drugs to build a healthy future for mankind.

Indexed as

Antineoplastic AgentsBiological ProductsCyanobacteriaDrug CarriersDrug Delivery SystemsHumansNanoparticlesNeoplasmsPharmaceutical PreparationsTheranostic NanomedicineAntineoplastic AgentsBiological ProductsDrug CarriersPharmaceutical Preparationsanti-tumorbioactivitycyanobacteriacytotoxicitynanoparticlesnatural compoundssecondary metabolites

Identifiers

PMID33466486
PMCPMC7796498
OpenAlexW3119336428

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.