Evidence map›Paper›PMID 33466478›Full record

ReviewDiagnostics (Basel, Switzerland)2021

Preoperative Evaluation of Coronary Artery Disease in Liver Transplant Candidates: Many Unanswered Questions in Clinical Practice.

Maria Bonou, Sophie Mavrogeni, Chris J Kapelios, Marina Skouloudi, Constantina Aggeli, Evangelos Cholongitas, George Papatheodoridis, John Barbetseas

Abstract readReview
In one paragraph

Review in Diagnostics (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Article
  2. Review
  3. Cardiology Assessment of Patients Undergoing Evaluation for Orthotopic Liver Transplantation.Journal of the Society for Cardiovascular Angiography & Interventions
    Review
  4. Article
  5. Review
  6. Cardiac Evaluation in Liver Transplant Candidates.Journal of clinical and experimental hepatology
    Review
  7. Demystifying the Heart Before Liver Transplant (LT).Journal of clinical and experimental hepatology
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Maria BonouDepartment of Cardiology, Laiko General Hospital, 11527 Athens, Greece.
Sophie MavrogeniDepartment of Cardiology, Onassis Cardiac Surgery Center, 17674 Athens, Greece.
Chris J KapeliosDepartment of Cardiology, Laiko General Hospital, 11527 Athens, Greece.ORCID 0000-0003-1616-6307
Marina SkouloudiDepartment of Cardiology, Laiko General Hospital, 11527 Athens, Greece.
Constantina AggeliFirst Department of Cardiology, Hippokration General Hospital, Medical School of National & Kapodistrian University, 11527 Athens, Greece.
Evangelos CholongitasFirst Department of Internal Medicine, Medical School of National & Kapodistrian University, 11527 Athens, Greece.
George PapatheodoridisDepartment of Gastroenterology, Laiko General Hospital, Medical School of National & Kapodistrian University, 11527 Athens, Greece.ORCID 0000-0002-3518-4060
John BarbetseasDepartment of Cardiology, Laiko General Hospital, 11527 Athens, Greece.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cardiovascular (CV) complications represent the first non-graft-related cause of death and the third overall cause of death among patients undergoing liver transplantation (LT). History of coronary artery disease is related to increased CV mortality following LT. Although it is of paramount importance to stratify CV risk in pre-LT patients, there is no consensus regarding the choice of the optimal non-invasive cardiac imaging test. Algorithms proposed by scientific associations include non-traditional risk factors, which are associated with increased cardiac risk profiles. Thus, an individualized pre-LT evaluation protocol should be followed. As the average age of patients undergoing LT and the number of candidates continue to rise, the "3 W" questions still remain unanswered, Who, Which and When? Who should be screened for coronary artery disease (CAD), which screening modality should be used and when should the asymptomatic waitlisted patients repeat cardiac evaluation? Prospective studies with large sample sizes are warranted to define an algorithm that can provide better risk stratification and more reliable survival prediction.

Indexed as

cardiovascular riskcoronary artery diseaseimagingliver transplantationprognosisrisk stratificationscreening

Identifiers

PMID33466478
PMCPMC7824885

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.