Evidence map›Paper›PMID 33466462›Full record

Trial reportNutrients2021

Consumption of a High-Protein Meal Replacement Leads to Higher Fat Oxidation, Suppression of Hunger, and Improved Metabolic Profile After an Exercise Session.

Camila L P Oliveira, Normand G Boulé, Aloys Berg, Arya M Sharma, Sarah A Elliott, Mario Siervo, Sunita Ghosh, Carla M Prado

Registry-linked trialOpen access · goldAbstract readRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in Nutrients, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05107583 (Comparing the Effects of a High- and Low-carbohydrate Pre-exercise Meal Relative to Fasting on Exercise Metabolism, Subsequent Appetite, and Energy Intake in Healthy Males.), which is not on this map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
1.7field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05107583 nacompletednot on this map

Comparing the Effects of a High- and Low-carbohydrate Pre-exercise Meal Relative to Fasting on Exercise Metabolism, Subsequent Appetite, and Energy Intake in Healthy Males.

TypeinterventionalSponsorNottingham Trent UniversityRan2021 to 2022Enrolled12ConditionsObesity, Metabolic SyndromeArmsLow-Carbohydrate Pre-Exercise Meal, High-Carbohydrate Pre-Exercise Meal, Fasted Exercise
3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 20 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 3 countries.

Camila L P OliveiraHuman Nutrition Research Unit, Department of Agricultural, Food & Nutritional Science, University of Alberta, Edmonton, AB T6G 2E1, Canada.
Normand G BouléAlberta Diabetes Institute, University of Alberta, Edmonton, AB T6G 2E1, Canada.ORCID 0000-0003-0256-702X
Aloys BergFaculty of Medicine, University of Freiburg, 79110 Freiburg, Germany.
Arya M SharmaDivision of Endocrinology & Metabolism, Department of Medicine, University of Alberta, Edmonton, AB T6G 2G3, Canada.
Sarah A ElliottHuman Nutrition Research Unit, Department of Agricultural, Food & Nutritional Science, University of Alberta, Edmonton, AB T6G 2E1, Canada.
Mario SiervoSchool of Life Sciences, Division of Physiology, Pharmacology and Neuroscience, University of Nottingham, Nottingham NG7 2UH, England, UK.
Sunita GhoshDepartment of Medical Oncology, University of Alberta, Edmonton, AB T6G 2R7, Canada.
Carla M PradoHuman Nutrition Research Unit, Department of Agricultural, Food & Nutritional Science, University of Alberta, Edmonton, AB T6G 2E1, Canada.
University of Alberta · CAUniversity of Freiburg · DEUniversity of Nottingham · GB

Funding

Almased Wellness GmbH N/A
6 · The paper itself

Abstract

The aim of this study was to compare the impact of a high-protein meal replacement (HP-MR) versus a control (CON) breakfast on exercise metabolism. In this acute, randomized controlled, cross-over study, participants were allocated into two isocaloric arms: (a) HP-MR: 30% carbohydrate, 43% protein, and 27% fat; (b) CON: 55% carbohydrate, 15% protein, and 30% fat. Following breakfast, participants performed a moderate-intensity aerobic exercise while inside a whole-body calorimetry unit. Energy expenditure, macronutrient oxidation, appetite sensations, and metabolic blood markers were assessed. Forty-three healthy, normal-weight adults (24 males) participated. Compared to the CON breakfast, the HP-MR produced higher fat oxidation (1.07 ± 0.33 g/session;

Indexed as

Diet, High-ProteinEnergy MetabolismExerciseFastingLipid MetabolismOxidation-ReductionAdultAppetiteBiomarkersBreakfastCross-Over StudiesEnergy IntakeFemaleHumansMaleYoung AdultBiomarkersappetiteenergy metabolismexercisemeal replacementprotein

Identifiers

PMID33466462
PMCPMC7824960
OpenAlexW3118264158

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.