Evidence map›Paper›PMID 33466434›Full record

ArticleInternational journal of molecular sciences2021

STAT3 Is an Upstream Regulator of

Huan Ou-Yang, Shinn-Chih Wu, Li-Ying Sung, Shiao-Hsuan Yang, Shang-Hsun Yang, Kowit-Yu Chong, Chuan-Mu Chen

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of molecular sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.7field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 8 citations in OpenAlex.

  1. Signaling pathway regulators in preimplantation embryos.Journal of molecular histology · 2024
    Review
  2. Article
  3. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 1 country.

Huan Ou-YangDepartment of Life Sciences, and Ph.D. Program in Translational Medicine, National Chung Hsing University, Taichung 402, Taiwan.
Shinn-Chih WuDepartment of Animal Science and Technology, National Taiwan University, Taipei 106, Taiwan.
Li-Ying SungInstitute of Biotechnology, National Taiwan University, Taipei 106, Taiwan.ORCID 0000-0003-1221-2476
Shiao-Hsuan YangDepartment of Life Sciences, and Ph.D. Program in Translational Medicine, National Chung Hsing University, Taichung 402, Taiwan.
Shang-Hsun YangDepartment of Physiology, National Cheng Kung University, Tainan 70101, Taiwan.
Kowit-Yu ChongDepartment of Medical Biotechnology and Laboratory Science, College of Medicine, Chang Gung University, Taoyuan 333, Taiwan.
Chuan-Mu ChenDepartment of Life Sciences, and Ph.D. Program in Translational Medicine, National Chung Hsing University, Taichung 402, Taiwan.ORCID 0000-0003-2461-9150
National Chung Hsing University · TWNational Taiwan University of Science and Technology · TWChang Gung University · TWNational Taiwan University · TW

Funding

The Ministry of Education of Taiwan MOE-109-S-0023-AThe Ministry of Science and Technology of Taiwan MOST-108-2313-B-005-039-MY3
6 · The paper itself

Abstract

The maternal-to-zygotic transition (MZT), which controls maternal signaling to synthesize zygotic gene products, promotes the preimplantation development of mouse zygotes to the two-cell stage. Our previous study reported that mouse granzyme g (Gzmg), a serine-type protease, is required for the MZT. In this study, we further identified the maternal factors that regulate the

Indexed as

AnimalsBlastocystCell NucleusEmbryonic DevelopmentFemaleGene Expression Regulation, DevelopmentalGranzymesGreen Fluorescent ProteinsMaleMiceMice, Inbred ICRPregnancyPromoter Regions, GeneticSTAT3 Transcription FactorTranscriptional ActivationTranscription FactorsGranzymesGreen Fluorescent ProteinsStat3 protein, mouseSTAT3 Transcription FactorTranscription Factorsgranzyme gmaternal-to-zygotic transitionpreimplantation embryoSTAT3

Identifiers

PMID33466434
PMCPMC7796490
OpenAlexW3119151250

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.