Evidence map›Paper›PMID 33466418›Full record

ArticleMaterials (Basel, Switzerland)2021

Lyophilized Polyvinylpyrrolidone Hydrogel for Culture of Human Oral Mucosa Stem Cells.

Carolina Oliver-Urrutia, Raúl Rosales Ibañez, Miriam V Flores-Merino, Lucy Vojtova, Jakub Salplachta, Ladislav Čelko, Jozef Kaiser, Edgar B Montufar

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Materials (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Carolina Oliver-UrrutiaFaculty of Chemistry, Autonomous University of the State of Mexico, Paseo Colon S/N, Toluca 50120, Mexico.ORCID 0000-0002-0722-0917
Raúl Rosales IbañezFaculty of Higher Studies Iztacala, National Autonomous University of Mexico, Los Reyes Iztacala 1, Mexico City 54090, Mexico.
Miriam V Flores-MerinoFaculty of Chemistry, Autonomous University of the State of Mexico, Paseo Colon S/N, Toluca 50120, Mexico.ORCID 0000-0003-0793-0940
Lucy VojtovaCentral European Institute of Technology, Brno University of Technology, Purkynova 123, 61200 Brno, Czech Republic.
Jakub SalplachtaCentral European Institute of Technology, Brno University of Technology, Purkynova 123, 61200 Brno, Czech Republic.ORCID 0000-0002-0149-7843
Ladislav ČelkoCentral European Institute of Technology, Brno University of Technology, Purkynova 123, 61200 Brno, Czech Republic.
Jozef KaiserCentral European Institute of Technology, Brno University of Technology, Purkynova 123, 61200 Brno, Czech Republic.ORCID 0000-0002-7397-125X
Edgar B MontufarCentral European Institute of Technology, Brno University of Technology, Purkynova 123, 61200 Brno, Czech Republic.ORCID 0000-0002-8122-4000

Funding

Consejo Nacional de Ciencia y Tecnología 2019-000029-01EXTV-00070Consejo Nacional de Ciencia y Tecnología 2020-000021-01EXTV-00235Ministerstvo Školství, Mládeže a Tělovýchovy LM2018110Ministerstvo Školství, Mládeže a Tělovýchovy LQ1601Universidad Autónoma del Estado de México 4993/2020/CIB
6 · The paper itself

Abstract

This work shows the synthesis of a polyvinylpyrrolidone (PVP) hydrogel by heat-activated polymerization and explores the production of hydrogels with an open porous network by lyophilisation to allow the three-dimensional culture of human oral mucosa stem cells (hOMSCs). The swollen hydrogel showed a storage modulus similar to oral mucosa and elastic solid rheological behaviour without sol transition. A comprehensive characterization of porosity by scanning electron microscopy, mercury intrusion porosimetry and nano-computed tomography (with spatial resolution below 1 μm) showed that lyophilisation resulted in the heterogeneous incorporation of closed oval-like pores in the hydrogel with broad size distribution (5 to 180 μm, d

Indexed as

hydrogellyophilisationnano-computed tomographyoral mucosapolyvinylpyrrolidoneporositystem cell

Identifiers

PMID33466418
PMCPMC7796241

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.