ArticleMicroorganisms2021
Dietary Organic Acids Modulate Gut Microbiota and Improve Growth Performance of Nursery Pigs.
Article in Microorganisms, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 35 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
35 citing papers in PubMed, 44 citations in OpenAlex.
- Comparative Effects of Different Dietary Acidifiers on Growth Performance and Intestinal Health in Weaned Piglets.Animals : an open access journal from MDPI · 2026Article
- Machine learning identifies key microbial signatures for Salmonella enteritidis colonization and persistence in broiler ceca.Poultry science · 2026Article
- Nutritional strategies using synbiotics and organic acids to enhance piglet post-weaning growth and gut health.Journal of animal science and technology · 2026Article
- Efficacy and Mechanisms of Butyric Acid Derivatives as Feed Additives in Weaned Piglet Nutrition: A Review.Antioxidants (Basel, Switzerland) · 2026Review
- A manually curated pig gut microbiome dataset for precision feeding.Scientific data · 2026Article
- The Effects of Dual-Yeast Compound Preparation on the Intestinal Health and Metabolism of Lambs.Animals : an open access journal from MDPI · 2026Article
- Organic acid-preserved grain improves growth and gut health in weanling pigs fed zinc oxide free diets.Scientific reports · 2025Article
- Single- and multiple-locus model genome-wide association study for growth traits in Dongliao black pigs.Animal bioscience · 2025Article
- Effects of paraformic acid supplementation, as an antibiotic replacement, on growth performance, intestinal morphology and gut microbiota of nursery pigs.Journal of animal science and technology · 2025Article
- Effects of Butyric Acid Supplementation on the Gut Microbiome and Growth Performance of Weanling Pigs Fed a Low-Crude Protein, Propionic Acid-Preserved Grain Diet.Microorganisms · 2025Article
- Antibiotics and Opportunities of Their Alternatives in Pig Production: Mechanisms Through Modulating Intestinal Microbiota on Intestinal Health and Growth.Antibiotics (Basel, Switzerland) · 2025Review
- Effects of organic acid-preserved cereal grains in sow diets during late gestation and lactation on the performance and faecal microbiota of sows and their offspring.Journal of animal science and biotechnology · 2025Article
- Effects of Red Clover Isoflavones on Growth Performance, Immune Function, and Cecal Microflora of Mice.Animals : an open access journal from MDPI · 2025Article
- Efficacy of supplemental amino acids with Corynebacterium glutamicum cell mass on growth and health of nursery pigs.Journal of animal science · 2025Article
- Herbal formula alleviates heat stress by improving physiological and biochemical attributes and modulating the rumen microbiome in dairy cows.Frontiers in veterinary science · 2025Article
- Microbiome analysis reveals dynamic changes of gut microbiota in Guizhou horse and Dutch Warmblood horses.Frontiers in microbiology · 2025Article
- Effects of dietary acidifiers and other low acid-binding capacity formulation strategies on weanling pig growth performance and fecal dry matter.Translational animal science · 2025Article
- Ultra-Processed Food and Gut Microbiota: Do Additives Affect Eubiosis? A Narrative Review.Nutrients · 2024Review
- Dietary Intervention of Benzoic Acid for Intestinal Health and Growth of Nursery Pigs.Animals : an open access journal from MDPI · 2024Review
- A Mixture of Formic Acid, Benzoic Acid, and Essential Oils Enhanced Growth Performance via Modulating Nutrient Uptake, Mitochondrion Metabolism, and Immunomodulation in Weaned Piglets.Antioxidants (Basel, Switzerland) · 2024Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
11 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Feed additives have been suggested to improve animal growth performance through modulating the gut microbiota. The hypothesis of this study was that the combination of two organic acids would exert synergistic effects on the growth performance and gut microbiota of weaning pigs. To test this hypothesis, we followed 398 weaning pigs from two university experiment stations (University of Illinois at Urbana-Champaign (UIUC) and University of Arkansas (UA)) to determine the effects of increasing levels (0%, 0.035%, 0.070%, and 0.105%) of sodium butyrate combined with 0.5% benzoic acid on the growth performance of nursery pigs. At the UA, an additional negative control diet was included and the gut microbiota analysis was carried out. At both universities, increasing levels of sodium butyrate in a diet containing 0.5% benzoic acid improved growth performance, which reached a plateau in the pigs fed 0.035% (SBA0.035) or 0.070% (SBA0.070) butyrate. Gut microbiota analysis revealed that pigs fed the SBA0.035 diet had more diverse microbiota and contained more potentially beneficial bacteria such as
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.