Evidence map›Paper›PMID 33466337›Full record

ArticleBrain sciences2021

Musical Training and Brain Volume in Older Adults.

Laura Chaddock-Heyman, Psyche Loui, Timothy B Weng, Robert Weisshappel, Edward McAuley, Arthur F Kramer

Registry-linked trialAbstract read
In one paragraph

Article in Brain sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06767410 (A Multi-domain Intervention to Constrast Cognitive Decline in Healthy Aging), which is not on this map. Cited by 36 papers.

0numbers the graph read from it
0cells of the map it votes in
36citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06767410 narecruitingnot on this mapstarted 2025, after this paper: background citation

A Multi-domain Intervention to Constrast Cognitive Decline in Healthy Aging

TypeinterventionalSponsorUniversity of BariRan2025 to 2027Enrolled100ConditionsHealthy Volunteer StudyArmsMultidomain Intervention, General activities
3 · Its place in the literature

Who cites it

36 citing papers in PubMed.

  1. Trial
  2. Characterizing Music Engagement and Reward in Individuals Across a Spectrum of Hearing Loss and Rehabilitation.Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Laura Chaddock-HeymanBeckman Institute, University of Illinois at Urbana-Champaign, Urbana, IL 61801, USA.
Psyche LouiDepartment of Psychology, Northeastern University, Boston, MA 02115, USA.ORCID 0000-0001-7664-6092
Timothy B WengDepartment of Diagnostic Medicine, The University of Texas at Austin, Austin, TX 78712, USA.
Robert WeisshappelBeckman Institute, University of Illinois at Urbana-Champaign, Urbana, IL 61801, USA.
Edward McAuleyBeckman Institute, University of Illinois at Urbana-Champaign, Urbana, IL 61801, USA.
Arthur F KramerBeckman Institute, University of Illinois at Urbana-Champaign, Urbana, IL 61801, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Musical practice, including musical training and musical performance, has been found to benefit cognitive function in older adults. Less is known about the role of musical experiences on brain structure in older adults. The present study examined the role of different types of musical behaviors on brain structure in older adults. We administered the Goldsmiths Musical Sophistication Index, a questionnaire that includes questions about a variety of musical behaviors, including performance on an instrument, musical practice, allocation of time to music, musical listening expertise, and emotional responses to music. We demonstrated that musical training, defined as the extent of musical training, musical practice, and musicianship, was positively and significantly associated with the volume of the inferior frontal cortex and parahippocampus. In addition, musical training was positively associated with volume of the posterior cingulate cortex, insula, and medial orbitofrontal cortex. Together, the present study suggests that musical behaviors relate to a circuit of brain regions involved in executive function, memory, language, and emotion. As gray matter often declines with age, our study has promising implications for the positive role of musical practice on aging brain health.

Indexed as

agingbrain structuremusicmusical trainingolder adults

Identifiers

PMID33466337
PMCPMC7824792

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.