Evidence map›Paper›PMID 33466307›Full record

ArticleDiagnostics (Basel, Switzerland)2021

Delta Radiomics Analysis for Local Control Prediction in Pancreatic Cancer Patients Treated Using Magnetic Resonance Guided Radiotherapy.

Davide Cusumano, Luca Boldrini, Poonam Yadav, Calogero Casà, Sangjune Laurence Lee, Angela Romano, Antonio Piras, Giuditta Chiloiro, Lorenzo Placidi, Francesco Catucci and 6 more

Open access · goldAbstract read
In one paragraph

Article in Diagnostics (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
32citing papers in PubMed, 3 pooled it
6.0field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

32 citing papers in PubMed, 3 syntheses or guidelines pooled it, 49 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Delta radiomics: a systematic review.La Radiologia medica · 2021
    Pooled it
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  20. Art and digital technologies to support resilience during the oncological journey: The Art4ART project.Technical innovations & patient support in radiation oncology · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 3 institutions in 3 countries.

Davide CusumanoFondazione Policlinico Universitario "Agostino Gemelli" IRCCS, 00168 Rome, Italy.ORCID 0000-0001-8626-0003
Luca BoldriniFondazione Policlinico Universitario "Agostino Gemelli" IRCCS, 00168 Rome, Italy.ORCID 0000-0002-5631-1575
Poonam YadavDepartment of Human Oncology, School of Medicine and Public Health, University of Wisconsin-Madison, 600 Highland Ave, Madison, WI 53792, USA.
Calogero CasàFondazione Policlinico Universitario "Agostino Gemelli" IRCCS, 00168 Rome, Italy.ORCID 0000-0001-5785-0549
Sangjune Laurence LeeDepartment of Oncology, University of Calgary, 1331 29 Street NW, Calgary, AB T2N 1N4, Canada.ORCID 0000-0002-1280-8109
Angela RomanoFondazione Policlinico Universitario "Agostino Gemelli" IRCCS, 00168 Rome, Italy.ORCID 0000-0001-9371-9951
Antonio PirasFondazione Policlinico Universitario "Agostino Gemelli" IRCCS, 00168 Rome, Italy.ORCID 0000-0003-2361-9327
Giuditta ChiloiroFondazione Policlinico Universitario "Agostino Gemelli" IRCCS, 00168 Rome, Italy.
Lorenzo PlacidiFondazione Policlinico Universitario "Agostino Gemelli" IRCCS, 00168 Rome, Italy.ORCID 0000-0003-0058-9145
Francesco CatucciFondazione Policlinico Universitario "Agostino Gemelli" IRCCS, 00168 Rome, Italy.ORCID 0000-0003-2619-4918
Claudio VottaFondazione Policlinico Universitario "Agostino Gemelli" IRCCS, 00168 Rome, Italy.ORCID 0000-0002-2836-1129
Gian Carlo MattiucciFondazione Policlinico Universitario "Agostino Gemelli" IRCCS, 00168 Rome, Italy.
Luca IndovinaFondazione Policlinico Universitario "Agostino Gemelli" IRCCS, 00168 Rome, Italy.
Maria Antonietta GambacortaFondazione Policlinico Universitario "Agostino Gemelli" IRCCS, 00168 Rome, Italy.
Michael BassettiDepartment of Human Oncology, School of Medicine and Public Health, University of Wisconsin-Madison, 600 Highland Ave, Madison, WI 53792, USA.
Vincenzo ValentiniFondazione Policlinico Universitario "Agostino Gemelli" IRCCS, 00168 Rome, Italy.
Agostino Gemelli University Polyclinic · ITUniversity of Wisconsin–Madison · USUniversity of Calgary · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The aim of this study is to investigate the role of Delta Radiomics analysis in the prediction of one-year local control (1yLC) in patients affected by locally advanced pancreatic cancer (LAPC) and treated using Magnetic Resonance guided Radiotherapy (MRgRT). A total of 35 patients from two institutions were enrolled: A 0.35 Tesla T2*/T1 MR image was acquired for each case during simulation and on each treatment fraction. Physical dose was converted in biologically effective dose (BED) to compensate for different radiotherapy schemes. Delta Radiomics analysis was performed considering the gross tumour volume (GTV) delineated on MR images acquired at BED of 20, 40, and 60 Gy. The performance of the delta features in predicting 1yLC was investigated in terms of Wilcoxon Mann-Whitney test and area under receiver operating characteristic (ROC) curve (AUC). The most significant feature in predicting 1yLC was the variation of cluster shade calculated at BED = 40 Gy, with a

Indexed as

magnetic resonanceMR-guided radiotherapypancreatic cancerradiomics

Identifiers

PMID33466307
PMCPMC7824764
OpenAlexW3119758656

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.